extramedullary hematopoiesis_Cdkn2b<tm1Bbd>/Cdkn2b<tm1Bbd>,Cdkn2c<tm1Bbd>/Cdkn2c<tm1Bbd>

http://metadb.riken.jp/0000240I129S1SvC57BL6Cdkn2btm1BbdCdkn2btm1BbdCdkn2ctm1BbdCdkn2ctm1BbdCdkn2btm1BbdCdkn2ctm1Bbd

extramedullary hematopoiesis_Cdkn2b<tm1Bbd>/Cdkn2b<tm1Bbd>,Cdkn2c<tm1Bbd>/Cdkn2c<tm1Bbd>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
  http://metadb.riken.jp/db/mgi_rdf/MGI:104737
• cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
  http://metadb.riken.jp/db/mgi_rdf/MGI:105388

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cdkn2b<tm1Bbd>/Cdkn2b<tm1Bbd>,Cdkn2c<tm1Bbd>/Cdkn2c<tm1Bbd>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cdkn2b<tm1Bbd>|Cdkn2c<tm1Bbd>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• extramedullary hematopoiesis
  http://purl.obolibrary.org/obo/MP_0000240

文献

http://purl.org/net/cito/citesAsAuthority

• E. Latres, et.al., Limited overlapping roles of P15(INK4b) and P18(INK4c) cell cycle inhibitors in proliferation and tumorigenesis., The EMBO journal, 2000, 19
  http://rdf.ncbi.nlm.nih.gov/pubmed/10880462