abnormal aorta morphology_Gt(ROSA)26Sor<tm1(EYFP)Cos>/Gt(ROSA)26Sor<+>,S1pr1<tm2Rlp>/S1pr1<tm2Rlp>,Tg(Cdh5-cre/ERT2)1Rha/0

http://metadb.riken.jp/0000272I129S6SvEvTac129X1SvJGtROSA26Sortm1EYFPCosGtROSA26SorS1pr1tm2RlpS1pr1tm2RlpTgCdh5creERT21Rha0GtROSA26SorS1pr1tm2RlpGtROSA26Sortm1EYFPCosTgCdh5creERT21Rha

abnormal aorta morphology_Gt(ROSA)26Sor<tm1(EYFP)Cos>/Gt(ROSA)26Sor<+>,S1pr1<tm2Rlp>/S1pr1<tm2Rlp>,Tg(Cdh5-cre/ERT2)1Rha/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735
• transgene insertion 1, Ralf H Adams
  http://metadb.riken.jp/db/mgi_rdf/MGI:3848980
• sphingosine-1-phosphate receptor 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1096355

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gt(ROSA)26Sor<tm1(EYFP)Cos>/Gt(ROSA)26Sor<+>,S1pr1<tm2Rlp>/S1pr1<tm2Rlp>,Tg(Cdh5-cre/ERT2)1Rha/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gt(ROSA)26Sor<+>|S1pr1<tm2Rlp>|Gt(ROSA)26Sor<tm1(EYFP)Cos>|Tg(Cdh5-cre/ERT2)1Rha

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * 129X1/SvJ

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal aorta morphology
  http://purl.obolibrary.org/obo/MP_0000272

文献

http://purl.org/net/cito/citesAsAuthority

• Konstantin. Gaengel, et.al., The sphingosine-1-phosphate receptor S1PR1 restricts sprouting angiogenesis by regulating the interplay between VE-cadherin and VEGFR2., Developmental cell, 2012, 23
  http://rdf.ncbi.nlm.nih.gov/pubmed/22975327