Konstantin. Gaengel, et.al., The sphingosine-1-phosphate receptor S1PR1 restricts sprouting angiogenesis by regulating the interplay between VE-cadherin and VEGFR2., Developmental cell, 2012, 23

http://rdf.ncbi.nlm.nih.gov/pubmed/22975327

Konstantin. Gaengel, et.al., The sphingosine-1-phosphate receptor S1PR1 restricts sprouting angiogenesis by regulating the interplay between VE-cadherin and VEGFR2., Developmental cell, 2012, 23

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal aorta morphology_S1pr1<tm1Rlp>/S1pr1<tm1Rlp>
  http://metadb.riken.jp/0000272I129S6SvEvTacS1pr1tm1RlpS1pr1tm1RlpS1pr1tm1Rlp
• abnormal artery morphology_S1pr1<tm1Rlp>/S1pr1<tm1Rlp>
  http://metadb.riken.jp/0002191I129S6SvEvTacS1pr1tm1RlpS1pr1tm1RlpS1pr1tm1Rlp
• abnormal aorta endothelium morphology_S1pr1<tm1Rlp>/S1pr1<tm1Rlp>
  http://metadb.riken.jp/0009864I129S6SvEvTacS1pr1tm1RlpS1pr1tm1RlpS1pr1tm1Rlp
• increased neuron apoptosis_S1pr1<tm1Rlp>/S1pr1<tm1Rlp>
  http://metadb.riken.jp/0003203I129S6SvEvTacS1pr1tm1RlpS1pr1tm1RlpS1pr1tm1Rlp
• embryonic lethality during organogenesis, complete penetrance_S1pr1<tm1Rlp>/S1pr1<tm1Rlp>
  http://metadb.riken.jp/0011098I129S6SvEvTacS1pr1tm1RlpS1pr1tm1RlpS1pr1tm1Rlp
• abnormal retinal vasculature morphology_Gt(ROSA)26Sor<tm1(EYFP)Cos>/Gt(ROSA)26Sor<+>,S1pr1<tm2Rlp>/S1pr1<tm2Rlp>,Tg(Cdh5-cre/ERT2)1Rha/0
  http://metadb.riken.jp/0002792I129S6SvEvTac129X1SvJGtROSA26Sortm1EYFPCosGtROSA26SorS1pr1tm2RlpS1pr1tm2RlpTgCdh5creERT21Rha0GtROSA26SorS1pr1tm2RlpGtROSA26Sortm1EYFPCosTgCdh5creERT21Rha
• abnormal aorta smooth muscle morphology_S1pr1<tm1Rlp>/S1pr1<tm1Rlp>
  http://metadb.riken.jp/0009865I129S6SvEvTacS1pr1tm1RlpS1pr1tm1RlpS1pr1tm1Rlp
• abnormal retinal vasculature morphology_Cdh5<tm1Dvst>/Cdh5<tm1Dvst>,Tg(Cdh5-cre/ERT2)1Rha/0
  http://metadb.riken.jp/0002792NSCdh5tm1DvstCdh5tm1DvstTgCdh5creERT21Rha0TgCdh5creERT21RhaCdh5tm1Dvst
• abnormal aorta morphology_Gt(ROSA)26Sor<tm1(EYFP)Cos>/Gt(ROSA)26Sor<+>,S1pr1<tm2Rlp>/S1pr1<tm2Rlp>,Tg(Cdh5-cre/ERT2)1Rha/0
  http://metadb.riken.jp/0000272I129S6SvEvTac129X1SvJGtROSA26Sortm1EYFPCosGtROSA26SorS1pr1tm2RlpS1pr1tm2RlpTgCdh5creERT21Rha0GtROSA26SorS1pr1tm2RlpGtROSA26Sortm1EYFPCosTgCdh5creERT21Rha
• abnormal vascular branching morphogenesis_S1pr1<tm1Rlp>/S1pr1<tm1Rlp>
  http://metadb.riken.jp/0003227I129S6SvEvTacS1pr1tm1RlpS1pr1tm1RlpS1pr1tm1Rlp
• increased vascular endothelial cell apoptosis_S1pr1<tm1Rlp>/S1pr1<tm1Rlp>
  http://metadb.riken.jp/0020321I129S6SvEvTacS1pr1tm1RlpS1pr1tm1RlpS1pr1tm1Rlp