increased granulocyte number_Hmox1<tm1.1Gkl>/Hmox1<tm1.1Gkl>,Lyz2<tm1(cre)Ifo>/Lyz2<+>

http://metadb.riken.jp/0000322I129129P2OlaHsdBALBcJC57BL6Hmox1tm11GklHmox1tm11GklLyz2tm1creIfoLyz2Lyz2Lyz2tm1creIfoHmox1tm11Gkl

increased granulocyte number_Hmox1<tm1.1Gkl>/Hmox1<tm1.1Gkl>,Lyz2<tm1(cre)Ifo>/Lyz2<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• lysozyme 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:96897
• heme oxygenase 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:96163

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Hmox1<tm1.1Gkl>/Hmox1<tm1.1Gkl>,Lyz2<tm1(cre)Ifo>/Lyz2<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Lyz2<+>|Lyz2<tm1(cre)Ifo>|Hmox1<tm1.1Gkl>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * 129P2/OlaHsd * BALB/cJ * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased granulocyte number
  http://purl.obolibrary.org/obo/MP_0000322

文献

http://purl.org/net/cito/citesAsAuthority

• Sotiria. Tzima, et.al., Myeloid heme oxygenase-1 regulates innate immunity and autoimmunity by modulating IFN-beta production., The Journal of experimental medicine, 2009, 206
  http://rdf.ncbi.nlm.nih.gov/pubmed/19398754