decreased bone marrow cell number_Adar<tm1.1Phs>/Adar<tm2Phs>,Tg(Tal1-cre/ERT)42-056Jrg/?

http://metadb.riken.jp/0000333I129S1Sv129X1SvJC57BL6Adartm11PhsAdartm2PhsTgTal1creERT42056JrgAdartm11PhsTgTal1creERT42056JrgAdartm2Phs

decreased bone marrow cell number_Adar<tm1.1Phs>/Adar<tm2Phs>,Tg(Tal1-cre/ERT)42-056Jrg/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• adenosine deaminase, RNA-specific
  http://metadb.riken.jp/db/mgi_rdf/MGI:1889575
• transgene insertion 42-056, Joachim R Gothert
  http://metadb.riken.jp/db/mgi_rdf/MGI:3579155

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Adar<tm1.1Phs>/Adar<tm2Phs>,Tg(Tal1-cre/ERT)42-056Jrg/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Adar<tm1.1Phs>|Tg(Tal1-cre/ERT)42-056Jrg|Adar<tm2Phs>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased bone marrow cell number
  http://purl.obolibrary.org/obo/MP_0000333

文献

http://purl.org/net/cito/citesAsAuthority

• Jochen C. Hartner, et.al., ADAR1 is essential for the maintenance of hematopoiesis and suppression of interferon signaling., Nature immunology, 2009, 10
  http://rdf.ncbi.nlm.nih.gov/pubmed/19060901