decreased granulocyte number_Gt(ROSA)26Sor<tm1(CTNNB1)Nerl>/Gt(ROSA)26Sor<tm1(CTNNB1)Nerl>,Tg(Mx1-cre)1Cgn/0

http://metadb.riken.jp/0000334I129P2OlaHsdBALBcC57BL6CBAGtROSA26Sortm1CTNNB1NerlGtROSA26Sortm1CTNNB1NerlTgMx1cre1Cgn0GtROSA26Sortm1CTNNB1NerlTgMx1cre1Cgn

decreased granulocyte number_Gt(ROSA)26Sor<tm1(CTNNB1)Nerl>/Gt(ROSA)26Sor<tm1(CTNNB1)Nerl>,Tg(Mx1-cre)1Cgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, University of Cologne
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176072
• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gt(ROSA)26Sor<tm1(CTNNB1)Nerl>/Gt(ROSA)26Sor<tm1(CTNNB1)Nerl>,Tg(Mx1-cre)1Cgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gt(ROSA)26Sor<tm1(CTNNB1)Nerl>|Tg(Mx1-cre)1Cgn

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * BALB/c * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased granulocyte number
  http://purl.obolibrary.org/obo/MP_0000334

文献

http://purl.org/net/cito/citesAsAuthority

• Peggy. Kirstetter, et.al., Activation of the canonical Wnt pathway leads to loss of hematopoietic stem cell repopulation and multilineage differentiation block., Nature immunology, 2006, 7
  http://rdf.ncbi.nlm.nih.gov/pubmed/16951689