Peggy. Kirstetter, et.al., Activation of the canonical Wnt pathway leads to loss of hematopoietic stem cell repopulation and multilineage differentiation block., Nature immunology, 2006, 7

http://rdf.ncbi.nlm.nih.gov/pubmed/16951689

Peggy. Kirstetter, et.al., Activation of the canonical Wnt pathway leads to loss of hematopoietic stem cell repopulation and multilineage differentiation block., Nature immunology, 2006, 7

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Gt(ROSA)26Sor<tm1(CTNNB1)Nerl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3664628
• Spi1<tm1.1Nerl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5787793

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal proerythroblast morphology_Gt(ROSA)26Sor<tm1(CTNNB1)Nerl>/Gt(ROSA)26Sor<tm1(CTNNB1)Nerl>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0002416I129P2OlaHsdBALBcC57BL6CBAGtROSA26Sortm1CTNNB1NerlGtROSA26Sortm1CTNNB1NerlTgMx1cre1Cgn0GtROSA26Sortm1CTNNB1NerlTgMx1cre1Cgn
• decreased leukocyte cell number_Gt(ROSA)26Sor<tm1(CTNNB1)Nerl>/Gt(ROSA)26Sor<tm1(CTNNB1)Nerl>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0000221I129P2OlaHsdBALBcC57BL6CBAGtROSA26Sortm1CTNNB1NerlGtROSA26Sortm1CTNNB1NerlTgMx1cre1Cgn0GtROSA26Sortm1CTNNB1NerlTgMx1cre1Cgn
• decreased double-negative T cell number_Gt(ROSA)26Sor<tm1(CTNNB1)Nerl>/Gt(ROSA)26Sor<tm1(CTNNB1)Nerl>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0005089I129P2OlaHsdBALBcC57BL6CBAGtROSA26Sortm1CTNNB1NerlGtROSA26Sortm1CTNNB1NerlTgMx1cre1Cgn0GtROSA26Sortm1CTNNB1NerlTgMx1cre1Cgn
• decreased erythrocyte cell number_Gt(ROSA)26Sor<tm1(CTNNB1)Nerl>/Gt(ROSA)26Sor<tm1(CTNNB1)Nerl>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0002875I129P2OlaHsdBALBcC57BL6CBAGtROSA26Sortm1CTNNB1NerlGtROSA26Sortm1CTNNB1NerlTgMx1cre1Cgn0GtROSA26Sortm1CTNNB1NerlTgMx1cre1Cgn
• premature death_Gt(ROSA)26Sor<tm1(CTNNB1)Nerl>/Gt(ROSA)26Sor<tm1(CTNNB1)Nerl>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0002083I129P2OlaHsdBALBcC57BL6CBAGtROSA26Sortm1CTNNB1NerlGtROSA26Sortm1CTNNB1NerlTgMx1cre1Cgn0GtROSA26Sortm1CTNNB1NerlTgMx1cre1Cgn
• thrombocytopenia_Gt(ROSA)26Sor<tm1(CTNNB1)Nerl>/Gt(ROSA)26Sor<tm1(CTNNB1)Nerl>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0003179I129P2OlaHsdBALBcC57BL6CBAGtROSA26Sortm1CTNNB1NerlGtROSA26Sortm1CTNNB1NerlTgMx1cre1Cgn0GtROSA26Sortm1CTNNB1NerlTgMx1cre1Cgn
• anemia_Gt(ROSA)26Sor<tm1(CTNNB1)Nerl>/Gt(ROSA)26Sor<tm1(CTNNB1)Nerl>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0001577I129P2OlaHsdBALBcC57BL6CBAGtROSA26Sortm1CTNNB1NerlGtROSA26Sortm1CTNNB1NerlTgMx1cre1Cgn0GtROSA26Sortm1CTNNB1NerlTgMx1cre1Cgn
• impaired myelopoiesis_Gt(ROSA)26Sor<tm1(CTNNB1)Nerl>/Gt(ROSA)26Sor<tm1(CTNNB1)Nerl>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0001602I129P2OlaHsdBALBcC57BL6CBAGtROSA26Sortm1CTNNB1NerlGtROSA26Sortm1CTNNB1NerlTgMx1cre1Cgn0GtROSA26Sortm1CTNNB1NerlTgMx1cre1Cgn
• thymus hypoplasia_Gt(ROSA)26Sor<tm1(CTNNB1)Nerl>/Gt(ROSA)26Sor<tm1(CTNNB1)Nerl>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0001823I129P2OlaHsdBALBcC57BL6CBAGtROSA26Sortm1CTNNB1NerlGtROSA26Sortm1CTNNB1NerlTgMx1cre1Cgn0GtROSA26Sortm1CTNNB1NerlTgMx1cre1Cgn
• decreased hemoglobin content_Gt(ROSA)26Sor<tm1(CTNNB1)Nerl>/Gt(ROSA)26Sor<tm1(CTNNB1)Nerl>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0002874I129P2OlaHsdBALBcC57BL6CBAGtROSA26Sortm1CTNNB1NerlGtROSA26Sortm1CTNNB1NerlTgMx1cre1Cgn0GtROSA26Sortm1CTNNB1NerlTgMx1cre1Cgn
• decreased granulocyte number_Gt(ROSA)26Sor<tm1(CTNNB1)Nerl>/Gt(ROSA)26Sor<tm1(CTNNB1)Nerl>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0000334I129P2OlaHsdBALBcC57BL6CBAGtROSA26Sortm1CTNNB1NerlGtROSA26Sortm1CTNNB1NerlTgMx1cre1Cgn0GtROSA26Sortm1CTNNB1NerlTgMx1cre1Cgn
• abnormal bone marrow cell number_Gt(ROSA)26Sor<tm1(CTNNB1)Nerl>/Gt(ROSA)26Sor<tm1(CTNNB1)Nerl>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0000172I129P2OlaHsdBALBcC57BL6CBAGtROSA26Sortm1CTNNB1NerlGtROSA26Sortm1CTNNB1NerlTgMx1cre1Cgn0GtROSA26Sortm1CTNNB1NerlTgMx1cre1Cgn
• arrested T cell differentiation_Gt(ROSA)26Sor<tm1(CTNNB1)Nerl>/Gt(ROSA)26Sor<tm1(CTNNB1)Nerl>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0001825I129P2OlaHsdBALBcC57BL6CBAGtROSA26Sortm1CTNNB1NerlGtROSA26Sortm1CTNNB1NerlTgMx1cre1Cgn0GtROSA26Sortm1CTNNB1NerlTgMx1cre1Cgn

class

http://purl.org/net/cito/citesAsAuthority

• Gt(ROSA)26Sor<tm1(CTNNB1)Nerl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3664628
• Spi1<tm1.1Nerl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5787793