increased cell proliferation_Cdkn2a<tm1Rdp>/Cdkn2a<tm1Rdp>,Dicer1<tm1Snj>/Dicer1<tm1Snj>

http://metadb.riken.jp/0000351I129Sv129S7SvEvBrdC57BL6SJLCdkn2atm1RdpCdkn2atm1RdpDicer1tm1SnjDicer1tm1SnjDicer1tm1SnjCdkn2atm1Rdp

increased cell proliferation_Cdkn2a<tm1Rdp>/Cdkn2a<tm1Rdp>,Dicer1<tm1Snj>/Dicer1<tm1Snj>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• dicer 1, ribonuclease type III
  http://metadb.riken.jp/db/mgi_rdf/MGI:2177178
• cyclin-dependent kinase inhibitor 2A
  http://metadb.riken.jp/db/mgi_rdf/MGI:104738

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cdkn2a<tm1Rdp>/Cdkn2a<tm1Rdp>,Dicer1<tm1Snj>/Dicer1<tm1Snj>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Dicer1<tm1Snj>|Cdkn2a<tm1Rdp>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129/Sv * 129S7/SvEvBrd * C57BL/6 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased cell proliferation
  http://purl.obolibrary.org/obo/MP_0000351

文献

http://purl.org/net/cito/citesAsAuthority

• Rajini. Mudhasani, et.al., Loss of miRNA biogenesis induces p19Arf-p53 signaling and senescence in primary cells., The Journal of cell biology, 2008, 181
  http://rdf.ncbi.nlm.nih.gov/pubmed/18591425