decreased cell proliferation_Cdk2<tm1Kald>/Cdk2<tm1Kald>,Cdk4<tm1Kiyo>/Cdk4<tm1Kiyo>,Cdkn1b<tm1Ako>/Cdkn1b<tm1Ako>

http://metadb.riken.jp/0000352I129S1SvC57BL6Cdk2tm1KaldCdk2tm1KaldCdk4tm1KiyoCdk4tm1KiyoCdkn1btm1AkoCdkn1btm1AkoCdk2tm1KaldCdkn1btm1AkoCdk4tm1Kiyo

decreased cell proliferation_Cdk2<tm1Kald>/Cdk2<tm1Kald>,Cdk4<tm1Kiyo>/Cdk4<tm1Kiyo>,Cdkn1b<tm1Ako>/Cdkn1b<tm1Ako>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• cyclin-dependent kinase inhibitor 1B
  http://metadb.riken.jp/db/mgi_rdf/MGI:104565
• cyclin-dependent kinase 4
  http://metadb.riken.jp/db/mgi_rdf/MGI:88357
• cyclin-dependent kinase 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:104772

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cdk2<tm1Kald>/Cdk2<tm1Kald>,Cdk4<tm1Kiyo>/Cdk4<tm1Kiyo>,Cdkn1b<tm1Ako>/Cdkn1b<tm1Ako>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cdk2<tm1Kald>|Cdkn1b<tm1Ako>|Cdk4<tm1Kiyo>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased cell proliferation
  http://purl.obolibrary.org/obo/MP_0000352

文献

http://purl.org/net/cito/citesAsAuthority

• Cyril. Berthet, et.al., Combined loss of Cdk2 and Cdk4 results in embryonic lethality and Rb hypophosphorylation., Developmental cell, 2006, 10
  http://rdf.ncbi.nlm.nih.gov/pubmed/16678773