decreased cell proliferation_Axin2<tm1.1(cre/ERT2/tdTomato)Smr>/Axin2<+>,Ctnnb1<tm2Kem>/Ctnnb1<tm2Kem>

http://metadb.riken.jp/0000352I129S2SvPasC57BL6Axin2tm11creERT2tdTomatoSmrAxin2Ctnnb1tm2KemCtnnb1tm2KemCtnnb1tm2KemAxin2tm11creERT2tdTomatoSmrAxin2

decreased cell proliferation_Axin2<tm1.1(cre/ERT2/tdTomato)Smr>/Axin2<+>,Ctnnb1<tm2Kem>/Ctnnb1<tm2Kem>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• axin 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:1270862
• catenin (cadherin associated protein), beta 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:88276

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Axin2<tm1.1(cre/ERT2/tdTomato)Smr>/Axin2<+>,Ctnnb1<tm2Kem>/Ctnnb1<tm2Kem>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Ctnnb1<tm2Kem>|Axin2<tm1.1(cre/ERT2/tdTomato)Smr>|Axin2<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased cell proliferation
  http://purl.obolibrary.org/obo/MP_0000352

文献

http://purl.org/net/cito/citesAsAuthority

• Yeon Sook. Choi, et.al., Distinct functions for Wnt/β-catenin in hair follicle stem cell proliferation and survival and interfollicular epidermal homeostasis., Cell stem cell, 2013, 13
  http://rdf.ncbi.nlm.nih.gov/pubmed/24315444