domed cranium_Egln1<tm1.1Brei>/Egln1<tm1.1Brei>,Hif1a<tm3Rsjo>/Hif1a<tm3Rsjo>,Tg(CD68-icre)1Bwlx/0

http://metadb.riken.jp/0000440I129S1Sv129X1SvJC57BL6Egln1tm11BreiEgln1tm11BreiHif1atm3RsjoHif1atm3RsjoTgCD68icre1Bwlx0TgCD68icre1BwlxEgln1tm11BreiHif1atm3Rsjo

domed cranium_Egln1<tm1.1Brei>/Egln1<tm1.1Brei>,Hif1a<tm3Rsjo>/Hif1a<tm3Rsjo>,Tg(CD68-icre)1Bwlx/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Ben Wielockx
  http://metadb.riken.jp/db/mgi_rdf/MGI:5474941
• hypoxia inducible factor 1, alpha subunit
  http://metadb.riken.jp/db/mgi_rdf/MGI:106918
• egl-9 family hypoxia-inducible factor 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1932286

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Egln1<tm1.1Brei>/Egln1<tm1.1Brei>,Hif1a<tm3Rsjo>/Hif1a<tm3Rsjo>,Tg(CD68-icre)1Bwlx/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(CD68-icre)1Bwlx|Egln1<tm1.1Brei>|Hif1a<tm3Rsjo>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• domed cranium
  http://purl.obolibrary.org/obo/MP_0000440

文献

http://purl.org/net/cito/citesAsAuthority

• Kristin. Franke, et.al., HIF-1α is a protective factor in conditional PHD2-deficient mice suffering from severe HIF-2α-induced excessive erythropoiesis., Blood, 2013, 121
  http://rdf.ncbi.nlm.nih.gov/pubmed/23264599