abnormal crypts of Lieberkuhn morphology_Mirc31<tm1.1Aru>/Mirc31<tm1.1Aru>,Tg(Vil1-cre)997Gum/0,Tg(Vil1-Lin28b,-tdTomato)LoAru/0

http://metadb.riken.jp/0000490I129S4SvJaeC57BL6C57BL6JSJLMirc31tm11AruMirc31tm11AruTgVil1cre997Gum0TgVil1Lin28btdTomatoLoAru0TgVil1Lin28btdTomatoLoAruTgVil1cre997GumMirc31tm11Aru

abnormal crypts of Lieberkuhn morphology_Mirc31<tm1.1Aru>/Mirc31<tm1.1Aru>,Tg(Vil1-cre)997Gum/0,Tg(Vil1-Lin28b,-tdTomato)LoAru/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion Lo, Anil K Rustgi
  http://metadb.riken.jp/db/mgi_rdf/MGI:5560193
• transgene insertion 997, Deborah L Gumucio
  http://metadb.riken.jp/db/mgi_rdf/MGI:2446957
• microRNA cluster 31, including Mirlet7c-2 through Mirlet7b
  http://metadb.riken.jp/db/mgi_rdf/MGI:5315466

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Mirc31<tm1.1Aru>/Mirc31<tm1.1Aru>,Tg(Vil1-cre)997Gum/0,Tg(Vil1-Lin28b,-tdTomato)LoAru/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Vil1-Lin28b,-tdTomato)LoAru|Tg(Vil1-cre)997Gum|Mirc31<tm1.1Aru>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * C57BL/6 * C57BL/6J * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal crypts of Lieberkuhn morphology
  http://purl.obolibrary.org/obo/MP_0000490

文献

http://purl.org/net/cito/citesAsAuthority

• Blair B. Madison, et.al., LIN28B promotes growth and tumorigenesis of the intestinal epithelium via Let-7., Genes & development, 2013, 27
  http://rdf.ncbi.nlm.nih.gov/pubmed/24142874