Blair B. Madison, et.al., LIN28B promotes growth and tumorigenesis of the intestinal epithelium via Let-7., Genes & development, 2013, 27

http://rdf.ncbi.nlm.nih.gov/pubmed/24142874

Blair B. Madison, et.al., LIN28B promotes growth and tumorigenesis of the intestinal epithelium via Let-7., Genes & development, 2013, 27

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Mirc31<tm1.1Aru>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5560203
• Tg(Vil1-Lin28b,-tdTomato)HiAru
  http://metadb.riken.jp/db/mgi_rdf/MGI:5560200
• Tg(tetO-Mirlet7a/Mir155,Vil1-rtTA)#Aru
  http://metadb.riken.jp/db/mgi_rdf/MGI:5560198
• Tg(Vil1-Lin28b,-tdTomato)LoAru
  http://metadb.riken.jp/db/mgi_rdf/MGI:5560202
• Tg(Vil1-Lin28b,-tdTomato)MedAru
  http://metadb.riken.jp/db/mgi_rdf/MGI:5560201

class

http://purl.org/net/cito/citesAsAuthority

• Mirc31<tm1.1Aru>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5560203
• Tg(Vil1-Lin28b,-tdTomato)HiAru
  http://metadb.riken.jp/db/mgi_rdf/MGI:5560200
• Tg(tetO-Mirlet7a/Mir155,Vil1-rtTA)#Aru
  http://metadb.riken.jp/db/mgi_rdf/MGI:5560198
• Tg(Vil1-Lin28b,-tdTomato)LoAru
  http://metadb.riken.jp/db/mgi_rdf/MGI:5560202
• Tg(Vil1-Lin28b,-tdTomato)MedAru
  http://metadb.riken.jp/db/mgi_rdf/MGI:5560201

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased Paneth cell number_Tg(Vil1-Lin28b,-tdTomato)LoAru/0
  http://metadb.riken.jp/0013486IC57BL6JSJLTgVil1Lin28btdTomatoLoAru0TgVil1Lin28btdTomatoLoAru
• increased small intestine adenocarcinoma incidence_Tg(Vil1-Lin28b,-tdTomato)HiAru/0
  http://metadb.riken.jp/0009309IC57BL6JSJLTgVil1Lin28btdTomatoHiAru0TgVil1Lin28btdTomatoHiAru
• abnormal small intestine crypts of Lieberkuhn morphology_Tg(Vil1-Lin28b,-tdTomato)MedAru/0
  http://metadb.riken.jp/0004841IC57BL6JSJLTgVil1Lin28btdTomatoMedAru0TgVil1Lin28btdTomatoMedAru
• abnormal intestinal goblet cell morphology_Tg(Vil1-Lin28b,-tdTomato)HiAru/0
  http://metadb.riken.jp/0003449IC57BL6JSJLTgVil1Lin28btdTomatoHiAru0TgVil1Lin28btdTomatoHiAru
• increased small intestine adenocarcinoma incidence_Tg(Vil1-Lin28b,-tdTomato)MedAru/0
  http://metadb.riken.jp/0009309IC57BL6JSJLTgVil1Lin28btdTomatoMedAru0TgVil1Lin28btdTomatoMedAru
• decreased Paneth cell number_Tg(Vil1-Lin28b,-tdTomato)MedAru/0
  http://metadb.riken.jp/0013486IC57BL6JSJLTgVil1Lin28btdTomatoMedAru0TgVil1Lin28btdTomatoMedAru
• abnormal small intestine morphology_Tg(Vil1-Lin28b,-tdTomato)MedAru/0
  http://metadb.riken.jp/0000496IC57BL6JSJLTgVil1Lin28btdTomatoMedAru0TgVil1Lin28btdTomatoMedAru
• increased intestinal adenoma incidence_Tg(Vil1-Lin28b,-tdTomato)HiAru/0
  http://metadb.riken.jp/0002404IC57BL6JSJLTgVil1Lin28btdTomatoHiAru0TgVil1Lin28btdTomatoHiAru
• abnormal small intestine morphology_Mirc31<tm1.1Aru>/Mirc31<tm1.1Aru>,Tg(Vil1-cre)997Gum/0
  http://metadb.riken.jp/0000496I129S4SvJaeC57BL6C57BL6JSJLMirc31tm11AruMirc31tm11AruTgVil1cre997Gum0TgVil1cre997GumMirc31tm11Aru
• abnormal intestine morphology_Mirc31<tm1.1Aru>/Mirc31<tm1.1Aru>,Tg(Vil1-cre)997Gum/0
  http://metadb.riken.jp/0000477I129S4SvJaeC57BL6C57BL6JSJLMirc31tm11AruMirc31tm11AruTgVil1cre997Gum0TgVil1cre997GumMirc31tm11Aru
• abnormal intestinal mucosa morphology_Tg(Vil1-Lin28b,-tdTomato)LoAru/0
  http://metadb.riken.jp/0000511IC57BL6JSJLTgVil1Lin28btdTomatoLoAru0TgVil1Lin28btdTomatoLoAru
• abnormal crypts of Lieberkuhn morphology_Mirc31<tm1.1Aru>/Mirc31<tm1.1Aru>,Tg(Vil1-cre)997Gum/0
  http://metadb.riken.jp/0000490I129S4SvJaeC57BL6C57BL6JSJLMirc31tm11AruMirc31tm11AruTgVil1cre997Gum0TgVil1cre997GumMirc31tm11Aru
• abnormal crypts of Lieberkuhn morphology_Mirc31<tm1.1Aru>/Mirc31<tm1.1Aru>,Tg(Vil1-cre)997Gum/0,Tg(Vil1-Lin28b,-tdTomato)LoAru/0
  http://metadb.riken.jp/0000490I129S4SvJaeC57BL6C57BL6JSJLMirc31tm11AruMirc31tm11AruTgVil1cre997Gum0TgVil1Lin28btdTomatoLoAru0TgVil1Lin28btdTomatoLoAruTgVil1cre997GumMirc31tm11Aru
• increased intestinal adenoma incidence_Tg(Vil1-Lin28b,-tdTomato)MedAru/0
  http://metadb.riken.jp/0002404IC57BL6JSJLTgVil1Lin28btdTomatoMedAru0TgVil1Lin28btdTomatoMedAru
• decreased Paneth cell number_Mirc31<tm1.1Aru>/Mirc31<tm1.1Aru>,Tg(Vil1-cre)997Gum/0,Tg(Vil1-Lin28b,-tdTomato)LoAru/0
  http://metadb.riken.jp/0013486I129S4SvJaeC57BL6C57BL6JSJLMirc31tm11AruMirc31tm11AruTgVil1cre997Gum0TgVil1Lin28btdTomatoLoAru0TgVil1Lin28btdTomatoLoAruTgVil1cre997GumMirc31tm11Aru
• decreased Paneth cell number_Mirc31<tm1.1Aru>/Mirc31<tm1.1Aru>,Tg(Vil1-cre)997Gum/0
  http://metadb.riken.jp/0013486I129S4SvJaeC57BL6C57BL6JSJLMirc31tm11AruMirc31tm11AruTgVil1cre997Gum0TgVil1cre997GumMirc31tm11Aru
• decreased Paneth cell number_Tg(Vil1-Lin28b,-tdTomato)HiAru/0
  http://metadb.riken.jp/0013486IC57BL6JSJLTgVil1Lin28btdTomatoHiAru0TgVil1Lin28btdTomatoHiAru
• abnormal small intestine morphology_Tg(Vil1-Lin28b,-tdTomato)LoAru/0
  http://metadb.riken.jp/0000496IC57BL6JSJLTgVil1Lin28btdTomatoLoAru0TgVil1Lin28btdTomatoLoAru
• abnormal jejunum crypts of Lieberkuhn morphology_Tg(Vil1-Lin28b,-tdTomato)HiAru/0
  http://metadb.riken.jp/0013483IC57BL6JSJLTgVil1Lin28btdTomatoHiAru0TgVil1Lin28btdTomatoHiAru
• abnormal intestinal mucosa morphology_Tg(Vil1-Lin28b,-tdTomato)MedAru/0
  http://metadb.riken.jp/0000511IC57BL6JSJLTgVil1Lin28btdTomatoMedAru0TgVil1Lin28btdTomatoMedAru