mammary gland hyperplasia_Chek1<tm2.1Sje>/Chek1<+>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(MMTV-cre)#Mam/0

http://metadb.riken.jp/0000630I129P2OlaHsdFVBChek1tm21SjeChek1Trp53tm1BrnTrp53tm1BrnTgMMTVcreMam0Trp53tm1BrnTgMMTVcreMamChek1Chek1tm21Sje

mammary gland hyperplasia_Chek1<tm2.1Sje>/Chek1<+>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(MMTV-cre)#Mam/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834
• transgene insertion, Lothar Hennighausen
  http://metadb.riken.jp/db/mgi_rdf/MGI:3802641
• checkpoint kinase 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1202065

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Chek1<tm2.1Sje>/Chek1<+>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(MMTV-cre)#Mam/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Trp53<tm1Brn>|Tg(MMTV-cre)#Mam|Chek1<+>|Chek1<tm2.1Sje>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * FVB

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• mammary gland hyperplasia
  http://purl.obolibrary.org/obo/MP_0000630

文献

http://purl.org/net/cito/citesAsAuthority

• T. Fishler, et.al., Genetic instability and mammary tumor formation in mice carrying mammary-specific disruption of Chk1 and p53., Oncogene, 2010, 29
  http://rdf.ncbi.nlm.nih.gov/pubmed/20473325