T. Fishler, et.al., Genetic instability and mammary tumor formation in mice carrying mammary-specific disruption of Chk1 and p53., Oncogene, 2010, 29

http://rdf.ncbi.nlm.nih.gov/pubmed/20473325

T. Fishler, et.al., Genetic instability and mammary tumor formation in mice carrying mammary-specific disruption of Chk1 and p53., Oncogene, 2010, 29

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal mammary gland alveolus morphology_Chek1<tm2.1Sje>/Chek1<tm2.1Sje>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(MMTV-cre)#Mam/0
  http://metadb.riken.jp/0009506I129P2OlaHsdFVBChek1tm21SjeChek1tm21SjeTrp53tm1BrnTrp53tm1BrnTgMMTVcreMam0TgMMTVcreMamTrp53tm1BrnChek1tm21Sje
• abnormal mammary gland morphology_Chek1<tm2.1Sje>/Chek1<+>,Tg(MMTV-cre)#Mam/0
  http://metadb.riken.jp/0000627IFVBChek1tm21SjeChek1TgMMTVcreMam0TgMMTVcreMamChek1Chek1tm21Sje
• increased mammary gland tumor incidence_Chek1<tm2.1Sje>/Chek1<tm2.1Sje>,Trp53<tm1Brn>/Trp53<+>,Tg(MMTV-cre)#Mam/0
  http://metadb.riken.jp/0010299I129P2OlaHsdFVBChek1tm21SjeChek1tm21SjeTrp53tm1BrnTrp53TgMMTVcreMam0Chek1tm21SjeTrp53Trp53tm1BrnTgMMTVcreMam
• abnormal tumor morphology_Chek1<tm2.1Sje>/Chek1<+>,Trp53<tm1Brn>/Trp53<+>,Tg(MMTV-cre)#Mam/0
  http://metadb.riken.jp/0003448I129P2OlaHsdFVBChek1tm21SjeChek1Trp53tm1BrnTrp53TgMMTVcreMam0Trp53Chek1tm21SjeChek1Trp53tm1BrnTgMMTVcreMam
• abnormal mammary gland alveolus morphology_Chek1<tm2.1Sje>/Chek1<+>,Trp53<tm1Brn>/Trp53<+>,Tg(MMTV-cre)#Mam/0
  http://metadb.riken.jp/0009506I129P2OlaHsdFVBChek1tm21SjeChek1Trp53tm1BrnTrp53TgMMTVcreMam0Trp53Chek1tm21SjeChek1Trp53tm1BrnTgMMTVcreMam
• increased lymphoma incidence_Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(MMTV-cre)#Mam/0
  http://metadb.riken.jp/0012431I129P2OlaHsdFVBTrp53tm1BrnTrp53tm1BrnTgMMTVcreMam0TgMMTVcreMamTrp53tm1Brn
• abnormal tumor vascularization_Chek1<tm2.1Sje>/Chek1<+>,Trp53<tm1Brn>/Trp53<+>,Tg(MMTV-cre)#Mam/0
  http://metadb.riken.jp/0010144I129P2OlaHsdFVBChek1tm21SjeChek1Trp53tm1BrnTrp53TgMMTVcreMam0Trp53Chek1tm21SjeChek1Trp53tm1BrnTgMMTVcreMam
• decreased tumor incidence_Chek1<tm2.1Sje>/Chek1<+>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(MMTV-cre)#Mam/0
  http://metadb.riken.jp/0002052I129P2OlaHsdFVBChek1tm21SjeChek1Trp53tm1BrnTrp53tm1BrnTgMMTVcreMam0Trp53tm1BrnTgMMTVcreMamChek1Chek1tm21Sje
• mammary gland hyperplasia_Chek1<tm2.1Sje>/Chek1<+>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(MMTV-cre)#Mam/0
  http://metadb.riken.jp/0000630I129P2OlaHsdFVBChek1tm21SjeChek1Trp53tm1BrnTrp53tm1BrnTgMMTVcreMam0Trp53tm1BrnTgMMTVcreMamChek1Chek1tm21Sje
• increased mammary gland tumor incidence_Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(MMTV-cre)#Mam/0
  http://metadb.riken.jp/0010299I129P2OlaHsdFVBTrp53tm1BrnTrp53tm1BrnTgMMTVcreMam0TgMMTVcreMamTrp53tm1Brn
• increased mammary adenocarcinoma incidence_Chek1<tm2.1Sje>/Chek1<+>,Trp53<tm1Brn>/Trp53<+>,Tg(MMTV-cre)#Mam/0
  http://metadb.riken.jp/0001883I129P2OlaHsdFVBChek1tm21SjeChek1Trp53tm1BrnTrp53TgMMTVcreMam0Trp53Chek1tm21SjeChek1Trp53tm1BrnTgMMTVcreMam
• abnormal mammary gland alveolus morphology_Chek1<tm2.1Sje>/Chek1<tm2.1Sje>,Trp53<tm1Brn>/Trp53<+>,Tg(MMTV-cre)#Mam/0
  http://metadb.riken.jp/0009506I129P2OlaHsdFVBChek1tm21SjeChek1tm21SjeTrp53tm1BrnTrp53TgMMTVcreMam0Chek1tm21SjeTrp53Trp53tm1BrnTgMMTVcreMam
• abnormal mammary gland morphology_Chek1<tm2.1Sje>/Chek1<tm2.1Sje>,Tg(MMTV-cre)#Mam/0
  http://metadb.riken.jp/0000627IFVBChek1tm21SjeChek1tm21SjeTgMMTVcreMam0Chek1tm21SjeTgMMTVcreMam
• abnormal mammary gland alveolus morphology_Chek1<tm2.1Sje>/Chek1<+>,Tg(MMTV-cre)#Mam/0
  http://metadb.riken.jp/0009506IFVBChek1tm21SjeChek1TgMMTVcreMam0TgMMTVcreMamChek1Chek1tm21Sje
• increased mammary gland tumor incidence_Chek1<tm2.1Sje>/Chek1<+>,Trp53<tm1Brn>/Trp53<+>,Tg(MMTV-cre)#Mam/0
  http://metadb.riken.jp/0010299I129P2OlaHsdFVBChek1tm21SjeChek1Trp53tm1BrnTrp53TgMMTVcreMam0Trp53Chek1tm21SjeChek1Trp53tm1BrnTgMMTVcreMam
• abnormal mammary gland alveolus morphology_Chek1<tm2.1Sje>/Chek1<+>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(MMTV-cre)#Mam/0
  http://metadb.riken.jp/0009506I129P2OlaHsdFVBChek1tm21SjeChek1Trp53tm1BrnTrp53tm1BrnTgMMTVcreMam0Trp53tm1BrnTgMMTVcreMamChek1Chek1tm21Sje
• decreased tumor incidence_Chek1<tm2.1Sje>/Chek1<tm2.1Sje>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(MMTV-cre)#Mam/0
  http://metadb.riken.jp/0002052I129P2OlaHsdFVBChek1tm21SjeChek1tm21SjeTrp53tm1BrnTrp53tm1BrnTgMMTVcreMam0TgMMTVcreMamTrp53tm1BrnChek1tm21Sje
• abnormal tumor morphology_Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(MMTV-cre)#Mam/0
  http://metadb.riken.jp/0003448I129P2OlaHsdFVBTrp53tm1BrnTrp53tm1BrnTgMMTVcreMam0TgMMTVcreMamTrp53tm1Brn
• increased mammary gland tumor incidence_Chek1<tm2.1Sje>/Chek1<+>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(MMTV-cre)#Mam/0
  http://metadb.riken.jp/0010299I129P2OlaHsdFVBChek1tm21SjeChek1Trp53tm1BrnTrp53tm1BrnTgMMTVcreMam0Trp53tm1BrnTgMMTVcreMamChek1Chek1tm21Sje
• abnormal branching of the mammary ductal tree_Chek1<tm2.1Sje>/Chek1<+>,Trp53<tm1Brn>/Trp53<+>,Tg(MMTV-cre)#Mam/0
  http://metadb.riken.jp/0000662I129P2OlaHsdFVBChek1tm21SjeChek1Trp53tm1BrnTrp53TgMMTVcreMam0Trp53Chek1tm21SjeChek1Trp53tm1BrnTgMMTVcreMam
• aneuploidy_Chek1<tm2.1Sje>/Chek1<+>,Trp53<tm1Brn>/Trp53<+>,Tg(MMTV-cre)#Mam/0
  http://metadb.riken.jp/0004024I129P2OlaHsdFVBChek1tm21SjeChek1Trp53tm1BrnTrp53TgMMTVcreMam0Trp53Chek1tm21SjeChek1Trp53tm1BrnTgMMTVcreMam
• abnormal chromosome morphology_Chek1<tm2.1Sje>/Chek1<+>,Trp53<tm1Brn>/Trp53<+>,Tg(MMTV-cre)#Mam/0
  http://metadb.riken.jp/0003702I129P2OlaHsdFVBChek1tm21SjeChek1Trp53tm1BrnTrp53TgMMTVcreMam0Trp53Chek1tm21SjeChek1Trp53tm1BrnTgMMTVcreMam
• abnormal mammary gland alveolus morphology_Chek1<tm2.1Sje>/Chek1<tm2.1Sje>,Tg(MMTV-cre)#Mam/0
  http://metadb.riken.jp/0009506IFVBChek1tm21SjeChek1tm21SjeTgMMTVcreMam0Chek1tm21SjeTgMMTVcreMam
• mammary gland hyperplasia_Chek1<tm2.1Sje>/Chek1<+>,Trp53<tm1Brn>/Trp53<+>,Tg(MMTV-cre)#Mam/0
  http://metadb.riken.jp/0000630I129P2OlaHsdFVBChek1tm21SjeChek1Trp53tm1BrnTrp53TgMMTVcreMam0Trp53Chek1tm21SjeChek1Trp53tm1BrnTgMMTVcreMam
• increased tumor incidence_Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(MMTV-cre)#Mam/0
  http://metadb.riken.jp/0002020I129P2OlaHsdFVBTrp53tm1BrnTrp53tm1BrnTgMMTVcreMam0TgMMTVcreMamTrp53tm1Brn
• abnormal tumor morphology_Chek1<tm2.1Sje>/Chek1<tm2.1Sje>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(MMTV-cre)#Mam/0
  http://metadb.riken.jp/0003448I129P2OlaHsdFVBChek1tm21SjeChek1tm21SjeTrp53tm1BrnTrp53tm1BrnTgMMTVcreMam0TgMMTVcreMamTrp53tm1BrnChek1tm21Sje

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD12403
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD12403