enlarged spleen_Kras<tm4Tyj>/Kras<+>,Tg(Mx1-cre)1Cgn/0

http://metadb.riken.jp/0000691I129S4SvJaeBALBcC57BL6CBAKrastm4TyjKrasTgMx1cre1Cgn0TgMx1cre1CgnKrastm4TyjKras

enlarged spleen_Kras<tm4Tyj>/Kras<+>,Tg(Mx1-cre)1Cgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, University of Cologne
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176072
• Kirsten rat sarcoma viral oncogene homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:96680

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Kras<tm4Tyj>/Kras<+>,Tg(Mx1-cre)1Cgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Mx1-cre)1Cgn|Kras<tm4Tyj>|Kras<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * BALB/c * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• enlarged spleen
  http://purl.obolibrary.org/obo/MP_0000691

文献

http://purl.org/net/cito/citesAsAuthority

• Iris T. Chan, et.al., Conditional expression of oncogenic K-ras from its endogenous promoter induces a myeloproliferative disease., The Journal of clinical investigation, 2004, 113
  http://rdf.ncbi.nlm.nih.gov/pubmed/14966562