Iris T. Chan, et.al., Conditional expression of oncogenic K-ras from its endogenous promoter induces a myeloproliferative disease., The Journal of clinical investigation, 2004, 113

http://rdf.ncbi.nlm.nih.gov/pubmed/14966562

Iris T. Chan, et.al., Conditional expression of oncogenic K-ras from its endogenous promoter induces a myeloproliferative disease., The Journal of clinical investigation, 2004, 113

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal hepatobiliary system morphology_Kras<tm4Tyj>/Kras<+>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0002138I129S4SvJaeBALBcC57BL6CBAKrastm4TyjKrasTgMx1cre1Cgn0TgMx1cre1CgnKrastm4TyjKras
• enlarged spleen_Kras<tm4Tyj>/Kras<+>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0000691I129S4SvJaeBALBcC57BL6CBAKrastm4TyjKrasTgMx1cre1Cgn0TgMx1cre1CgnKrastm4TyjKras
• premature death_Kras<tm4Tyj>/Kras<+>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0002083I129S4SvJaeBALBcC57BL6CBAKrastm4TyjKrasTgMx1cre1Cgn0TgMx1cre1CgnKrastm4TyjKras
• increased leukocyte cell number_Kras<tm4Tyj>/Kras<+>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0000218I129S4SvJaeBALBcC57BL6CBAKrastm4TyjKrasTgMx1cre1Cgn0TgMx1cre1CgnKrastm4TyjKras
• increased granulocyte number_Kras<tm4Tyj>/Kras<+>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0000322I129S4SvJaeBALBcC57BL6CBAKrastm4TyjKrasTgMx1cre1Cgn0TgMx1cre1CgnKrastm4TyjKras
• increased lymphoblastic lymphoma incidence_Kras<tm4Tyj>/Kras<+>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0009320I129S4SvJaeBALBcC57BL6CBAKrastm4TyjKrasTgMx1cre1Cgn0TgMx1cre1CgnKrastm4TyjKras
• anemia_Kras<tm4Tyj>/Kras<+>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0001577I129S4SvJaeBALBcC57BL6CBAKrastm4TyjKrasTgMx1cre1Cgn0TgMx1cre1CgnKrastm4TyjKras
• increased oral papilloma incidence_Kras<tm4Tyj>/Kras<+>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0003752I129S4SvJaeBALBcC57BL6CBAKrastm4TyjKrasTgMx1cre1Cgn0TgMx1cre1CgnKrastm4TyjKras
• abnormal definitive hematopoiesis_Kras<tm4Tyj>/Kras<+>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0002123I129S4SvJaeBALBcC57BL6CBAKrastm4TyjKrasTgMx1cre1Cgn0TgMx1cre1CgnKrastm4TyjKras
• myeloid hyperplasia_Kras<tm4Tyj>/Kras<+>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0010373I129S4SvJaeBALBcC57BL6CBAKrastm4TyjKrasTgMx1cre1Cgn0TgMx1cre1CgnKrastm4TyjKras
• abnormal myelopoiesis_Kras<tm4Tyj>/Kras<+>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0001601I129S4SvJaeBALBcC57BL6CBAKrastm4TyjKrasTgMx1cre1Cgn0TgMx1cre1CgnKrastm4TyjKras
• decreased hematocrit_Kras<tm4Tyj>/Kras<+>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0000208I129S4SvJaeBALBcC57BL6CBAKrastm4TyjKrasTgMx1cre1Cgn0TgMx1cre1CgnKrastm4TyjKras
• increased esophageal papilloma incidence_Kras<tm4Tyj>/Kras<+>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0003277I129S4SvJaeBALBcC57BL6CBAKrastm4TyjKrasTgMx1cre1Cgn0TgMx1cre1CgnKrastm4TyjKras
• cachexia_Kras<tm4Tyj>/Kras<+>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0005150I129S4SvJaeBALBcC57BL6CBAKrastm4TyjKrasTgMx1cre1Cgn0TgMx1cre1CgnKrastm4TyjKras
• extramedullary hematopoiesis_Kras<tm4Tyj>/Kras<+>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0000240I129S4SvJaeBALBcC57BL6CBAKrastm4TyjKrasTgMx1cre1Cgn0TgMx1cre1CgnKrastm4TyjKras
• increased spleen red pulp amount_Kras<tm4Tyj>/Kras<+>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0008476I129S4SvJaeBALBcC57BL6CBAKrastm4TyjKrasTgMx1cre1Cgn0TgMx1cre1CgnKrastm4TyjKras
• increased papilloma incidence_Kras<tm4Tyj>/Kras<+>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0002014I129S4SvJaeBALBcC57BL6CBAKrastm4TyjKrasTgMx1cre1Cgn0TgMx1cre1CgnKrastm4TyjKras
• ruffled hair_Kras<tm4Tyj>/Kras<+>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0000420I129S4SvJaeBALBcC57BL6CBAKrastm4TyjKrasTgMx1cre1Cgn0TgMx1cre1CgnKrastm4TyjKras
• increased skin papilloma incidence_Kras<tm4Tyj>/Kras<+>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0002051I129S4SvJaeBALBcC57BL6CBAKrastm4TyjKrasTgMx1cre1Cgn0TgMx1cre1CgnKrastm4TyjKras
• increased lung adenoma incidence_Kras<tm4Tyj>/Kras<+>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0002048I129S4SvJaeBALBcC57BL6CBAKrastm4TyjKrasTgMx1cre1Cgn0TgMx1cre1CgnKrastm4TyjKras
• lymphoid hyperplasia_Kras<tm4Tyj>/Kras<+>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0000688I129S4SvJaeBALBcC57BL6CBAKrastm4TyjKrasTgMx1cre1Cgn0TgMx1cre1CgnKrastm4TyjKras
• abnormal erythrocyte morphology_Kras<tm4Tyj>/Kras<+>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0002447I129S4SvJaeBALBcC57BL6CBAKrastm4TyjKrasTgMx1cre1Cgn0TgMx1cre1CgnKrastm4TyjKras