enlarged thymus_Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(CD2-icre)4Kio/0

http://metadb.riken.jp/0000709I129S4SvJaeC57BL6C57BL10CBACaPtentm1HwuPtentm1HwuTgCD2icre4Kio0TgCD2icre4KioPtentm1Hwu

enlarged thymus_Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(CD2-icre)4Kio/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• phosphatase and tensin homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:109583
• transgene insertion 4, Dimitris Kioussis
  http://metadb.riken.jp/db/mgi_rdf/MGI:2449946

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(CD2-icre)4Kio/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(CD2-icre)4Kio|Pten<tm1Hwu>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * C57BL/6 * C57BL/10 * CBA/Ca

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• enlarged thymus
  http://purl.obolibrary.org/obo/MP_0000709

文献

http://purl.org/net/cito/citesAsAuthority

• M. Kraus, et.al., Protein kinase N3 deficiency impedes PI3-kinase pathway-driven leukemogenesis without affecting normal hematopoiesis., Leukemia, 2015, 29
  http://rdf.ncbi.nlm.nih.gov/pubmed/25234167