M. Kraus, et.al., Protein kinase N3 deficiency impedes PI3-kinase pathway-driven leukemogenesis without affecting normal hematopoiesis., Leukemia, 2015, 29

http://rdf.ncbi.nlm.nih.gov/pubmed/25234167

M. Kraus, et.al., Protein kinase N3 deficiency impedes PI3-kinase pathway-driven leukemogenesis without affecting normal hematopoiesis., Leukemia, 2015, 29

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Pkn3<tm1.1Mrl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5688854
• Pkn3<tm1.2Mrl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5688856

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• extramedullary hematopoiesis_Pkn3<tm1.1Mrl>/Pkn3<+>,Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0000240I129S4SvJaeC57BL6CBAJPkn3tm11MrlPkn3Ptentm1HwuPtentm1HwuTgMx1cre1Cgn0Ptentm1HwuPkn3tm11MrlPkn3TgMx1cre1Cgn
• extramedullary hematopoiesis_Pkn3<tm1.1Mrl>/Pkn3<tm1.1Mrl>,Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0000240I129S4SvJaeC57BL6CBAJPkn3tm11MrlPkn3tm11MrlPtentm1HwuPtentm1HwuTgMx1cre1Cgn0Ptentm1HwuPkn3tm11MrlTgMx1cre1Cgn
• enlarged spleen_Pkn3<tm1.1Mrl>/Pkn3<+>,Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0000691I129S4SvJaeC57BL6CBAJPkn3tm11MrlPkn3Ptentm1HwuPtentm1HwuTgMx1cre1Cgn0Ptentm1HwuPkn3tm11MrlPkn3TgMx1cre1Cgn
• enlarged spleen_Pkn3<tm1.1Mrl>/Pkn3<tm1.1Mrl>,Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0000691I129S4SvJaeC57BL6CBAJPkn3tm11MrlPkn3tm11MrlPtentm1HwuPtentm1HwuTgMx1cre1Cgn0Ptentm1HwuPkn3tm11MrlTgMx1cre1Cgn
• enlarged thymus_Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(CD2-icre)4Kio/0
  http://metadb.riken.jp/0000709I129S4SvJaeC57BL6C57BL10CBACaPtentm1HwuPtentm1HwuTgCD2icre4Kio0TgCD2icre4KioPtentm1Hwu
• enlarged thymus_Pkn3<tm1.1Mrl>/Pkn3<+>,Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0000709I129S4SvJaeC57BL6CBAJPkn3tm11MrlPkn3Ptentm1HwuPtentm1HwuTgMx1cre1Cgn0Ptentm1HwuPkn3tm11MrlPkn3TgMx1cre1Cgn
他8件を見る
• enlarged thymus_Pkn3<tm1.1Mrl>/Pkn3<tm1.1Mrl>,Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0000709I129S4SvJaeC57BL6CBAJPkn3tm11MrlPkn3tm11MrlPtentm1HwuPtentm1HwuTgMx1cre1Cgn0Ptentm1HwuPkn3tm11MrlTgMx1cre1Cgn
• premature death_Pkn3<tm1.1Mrl>/Pkn3<+>,Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0002083I129S4SvJaeC57BL6CBAJPkn3tm11MrlPkn3Ptentm1HwuPtentm1HwuTgMx1cre1Cgn0Ptentm1HwuPkn3tm11MrlPkn3TgMx1cre1Cgn
• premature death_Pkn3<tm1.1Mrl>/Pkn3<tm1.1Mrl>,Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0002083I129S4SvJaeC57BL6CBAJPkn3tm11MrlPkn3tm11MrlPtentm1HwuPtentm1HwuTgMx1cre1Cgn0Ptentm1HwuPkn3tm11MrlTgMx1cre1Cgn
• no abnormal phenotype detected_Pkn3<tm1.2Mrl>/Pkn3<tm1.2Mrl>
  http://metadb.riken.jp/0002169C57BL6Pkn3tm12MrlPkn3tm12MrlPkn3tm12MrlPkn3tm12Mrl
• increased hemolymphoid system tumor incidence_Pkn3<tm1.1Mrl>/Pkn3<+>,Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0010296I129S4SvJaeC57BL6CBAJPkn3tm11MrlPkn3Ptentm1HwuPtentm1HwuTgMx1cre1Cgn0Ptentm1HwuPkn3tm11MrlPkn3TgMx1cre1Cgn
• increased hemolymphoid system tumor incidence_Pkn3<tm1.1Mrl>/Pkn3<tm1.1Mrl>,Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0010296I129S4SvJaeC57BL6CBAJPkn3tm11MrlPkn3tm11MrlPtentm1HwuPtentm1HwuTgMx1cre1Cgn0Ptentm1HwuPkn3tm11MrlTgMx1cre1Cgn
• increased acute lymphoblastic leukemia incidence_Pkn3<tm1.1Mrl>/Pkn3<+>,Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0010336I129S4SvJaeC57BL6CBAJPkn3tm11MrlPkn3Ptentm1HwuPtentm1HwuTgMx1cre1Cgn0Ptentm1HwuPkn3tm11MrlPkn3TgMx1cre1Cgn
• increased acute lymphoblastic leukemia incidence_Pkn3<tm1.1Mrl>/Pkn3<tm1.1Mrl>,Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0010336I129S4SvJaeC57BL6CBAJPkn3tm11MrlPkn3tm11MrlPtentm1HwuPtentm1HwuTgMx1cre1Cgn0Ptentm1HwuPkn3tm11MrlTgMx1cre1Cgn

class

http://purl.org/net/cito/citesAsAuthority

• Pkn3<tm1.1Mrl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5688854
• Pkn3<tm1.2Mrl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5688856