abnormal skeletal muscle morphology_Prkab1<tm1Grst>/Prkab1<tm1Grst>,Prkab2<tm1Grst>/Prkab2<tm1Grst>,Tg(Ckmm-cre)5Khn/0

http://metadb.riken.jp/0000759IC57BL6FVBPrkab1tm1GrstPrkab1tm1GrstPrkab2tm1GrstPrkab2tm1GrstTgCkmmcre5Khn0Prkab1tm1GrstPrkab2tm1GrstTgCkmmcre5Khn

abnormal skeletal muscle morphology_Prkab1<tm1Grst>/Prkab1<tm1Grst>,Prkab2<tm1Grst>/Prkab2<tm1Grst>,Tg(Ckmm-cre)5Khn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• protein kinase, AMP-activated, beta 1 non-catalytic subunit
  http://metadb.riken.jp/db/mgi_rdf/MGI:1336167
• protein kinase, AMP-activated, beta 2 non-catalytic subunit
  http://metadb.riken.jp/db/mgi_rdf/MGI:1336185
• transgene insertion 5, C Ronald Kahn
  http://metadb.riken.jp/db/mgi_rdf/MGI:2182093

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Prkab1<tm1Grst>/Prkab1<tm1Grst>,Prkab2<tm1Grst>/Prkab2<tm1Grst>,Tg(Ckmm-cre)5Khn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Prkab1<tm1Grst>|Prkab2<tm1Grst>|Tg(Ckmm-cre)5Khn

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * FVB

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal skeletal muscle morphology
  http://purl.obolibrary.org/obo/MP_0000759

文献

http://purl.org/net/cito/citesAsAuthority

• Hayley M. O'Neill, et.al., AMP-activated protein kinase (AMPK) beta1beta2 muscle null mice reveal an essential role for AMPK in maintaining mitochondrial content and glucose uptake during exercise., Proceedings of the National Academy of Sciences of the United States of America, 2011, 108
  http://rdf.ncbi.nlm.nih.gov/pubmed/21896769