Hayley M. O'Neill, et.al., AMP-activated protein kinase (AMPK) beta1beta2 muscle null mice reveal an essential role for AMPK in maintaining mitochondrial content and glucose uptake during exercise., Proceedings of the National Academy of Sciences of the United States of America, 2011, 108

http://rdf.ncbi.nlm.nih.gov/pubmed/21896769

Hayley M. O'Neill, et.al., AMP-activated protein kinase (AMPK) beta1beta2 muscle null mice reveal an essential role for AMPK in maintaining mitochondrial content and glucose uptake during exercise., Proceedings of the National Academy of Sciences of the United States of America, 2011, 108

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Prkab1<tm1Grst>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5293373

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased circulating glucose level_Prkab1<tm1Grst>/Prkab1<tm1Grst>,Prkab2<tm1Grst>/Prkab2<tm1Grst>,Tg(Ckmm-cre)5Khn/0
  http://metadb.riken.jp/0005559IC57BL6FVBPrkab1tm1GrstPrkab1tm1GrstPrkab2tm1GrstPrkab2tm1GrstTgCkmmcre5Khn0Prkab1tm1GrstPrkab2tm1GrstTgCkmmcre5Khn
• decreased muscle cell glucose uptake_Prkab1<tm1Grst>/Prkab1<tm1Grst>,Prkab2<tm1Grst>/Prkab2<tm1Grst>,Tg(Ckmm-cre)5Khn/0
  http://metadb.riken.jp/0030022IC57BL6FVBPrkab1tm1GrstPrkab1tm1GrstPrkab2tm1GrstPrkab2tm1GrstTgCkmmcre5Khn0Prkab1tm1GrstPrkab2tm1GrstTgCkmmcre5Khn
• muscle fatigue_Prkab1<tm1Grst>/Prkab1<tm1Grst>,Prkab2<tm1Grst>/Prkab2<tm1Grst>,Tg(Ckmm-cre)5Khn/0
  http://metadb.riken.jp/0003646IC57BL6FVBPrkab1tm1GrstPrkab1tm1GrstPrkab2tm1GrstPrkab2tm1GrstTgCkmmcre5Khn0Prkab1tm1GrstPrkab2tm1GrstTgCkmmcre5Khn
• lethality, complete penetrance_Prkab1<tm1Eihl>/Prkab1<tm1Eihl>,Prkab2<tm1.1Grst>/Prkab2<tm1.1Grst>
  http://metadb.riken.jp/0011400IC57BL6Prkab1tm1EihlPrkab1tm1EihlPrkab2tm11GrstPrkab2tm11GrstPrkab2tm11GrstPrkab1tm1Eihl
• impaired exercise endurance_Prkab1<tm1Grst>/Prkab1<tm1Grst>,Prkab2<tm1Grst>/Prkab2<tm1Grst>,Tg(Ckmm-cre)5Khn/0
  http://metadb.riken.jp/0012106IC57BL6FVBPrkab1tm1GrstPrkab1tm1GrstPrkab2tm1GrstPrkab2tm1GrstTgCkmmcre5Khn0Prkab1tm1GrstPrkab2tm1GrstTgCkmmcre5Khn
• impaired exercise endurance_Prkab2<tm1Grst>/Prkab2<tm1Grst>,Tg(Ckmm-cre)5Khn/0
  http://metadb.riken.jp/0012106IC57BL6FVBPrkab2tm1GrstPrkab2tm1GrstTgCkmmcre5Khn0Prkab2tm1GrstTgCkmmcre5Khn
• abnormal skeletal muscle morphology_Prkab1<tm1Grst>/Prkab1<tm1Grst>,Prkab2<tm1Grst>/Prkab2<tm1Grst>,Tg(Ckmm-cre)5Khn/0
  http://metadb.riken.jp/0000759IC57BL6FVBPrkab1tm1GrstPrkab1tm1GrstPrkab2tm1GrstPrkab2tm1GrstTgCkmmcre5Khn0Prkab1tm1GrstPrkab2tm1GrstTgCkmmcre5Khn
• hypoactivity_Prkab1<tm1Grst>/Prkab1<tm1Grst>,Prkab2<tm1Grst>/Prkab2<tm1Grst>,Tg(Ckmm-cre)5Khn/0
  http://metadb.riken.jp/0001402IC57BL6FVBPrkab1tm1GrstPrkab1tm1GrstPrkab2tm1GrstPrkab2tm1GrstTgCkmmcre5Khn0Prkab1tm1GrstPrkab2tm1GrstTgCkmmcre5Khn
• abnormal enzyme/coenzyme activity_Prkab1<tm1Grst>/Prkab1<tm1Grst>,Prkab2<tm1Grst>/Prkab2<tm1Grst>,Tg(Ckmm-cre)5Khn/0
  http://metadb.riken.jp/0005584IC57BL6FVBPrkab1tm1GrstPrkab1tm1GrstPrkab2tm1GrstPrkab2tm1GrstTgCkmmcre5Khn0Prkab1tm1GrstPrkab2tm1GrstTgCkmmcre5Khn

class

http://purl.org/net/cito/citesAsAuthority

• Prkab1<tm1Grst>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5293373