abnormal forebrain morphology_Shh<tm1Chg>/Shh<tm1Chg>,Zic2<Ku>/Zic2<Ku>

http://metadb.riken.jp/0000783I129S1Sv129X1SvJBALBcAnNCrlC3HHeHShhtm1ChgShhtm1ChgZic2KuZic2KuZic2KuShhtm1Chg

abnormal forebrain morphology_Shh<tm1Chg>/Shh<tm1Chg>,Zic2<Ku>/Zic2<Ku>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• zinc finger protein of the cerebellum 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:106679
• sonic hedgehog
  http://metadb.riken.jp/db/mgi_rdf/MGI:98297

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Shh<tm1Chg>/Shh<tm1Chg>,Zic2<Ku>/Zic2<Ku>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Zic2<Ku>|Shh<tm1Chg>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * BALB/cAnNCrl * C3H/HeH

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal forebrain morphology
  http://purl.obolibrary.org/obo/MP_0000783

文献

http://purl.org/net/cito/citesAsAuthority

• Nicholas. Warr, et.al., Zic2-associated holoprosencephaly is caused by a transient defect in the organizer region during gastrulation., Human molecular genetics, 2008, 17
  http://rdf.ncbi.nlm.nih.gov/pubmed/18617531