abnormal telencephalon morphology_Shh<tm2Chg>/Shh<+>,Tg(Sox2-cre)1Amc/0

http://metadb.riken.jp/0000787I129S1Sv129X1SvJC57BL6CBAShhtm2ChgShhTgSox2cre1Amc0ShhTgSox2cre1AmcShhtm2Chg

abnormal telencephalon morphology_Shh<tm2Chg>/Shh<+>,Tg(Sox2-cre)1Amc/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• sonic hedgehog
  http://metadb.riken.jp/db/mgi_rdf/MGI:98297
• transgene insertion 1, Andrew P McMahon
  http://metadb.riken.jp/db/mgi_rdf/MGI:2656537

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Shh<tm2Chg>/Shh<+>,Tg(Sox2-cre)1Amc/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Shh<+>|Tg(Sox2-cre)1Amc|Shh<tm2Chg>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal telencephalon morphology
  http://purl.obolibrary.org/obo/MP_0000787

文献

http://purl.org/net/cito/citesAsAuthority

• Xi. Huang, et.al., Ectopic sonic hedgehog signaling impairs telencephalic dorsal midline development: implication for human holoprosencephaly., Human molecular genetics, 2007, 16
  http://rdf.ncbi.nlm.nih.gov/pubmed/17468181