abnormal hypothalamus morphology_Dmxl2<tm1c(EUCOMM)Wtsi>/Dmxl2<+>,Tg(Nes-cre)1Atp/0

http://metadb.riken.jp/0000837IC57BL6NFVBNDmxl2tm1cEUCOMMWtsiDmxl2TgNescre1Atp0Dmxl2Dmxl2tm1cEUCOMMWtsiTgNescre1Atp

abnormal hypothalamus morphology_Dmxl2<tm1c(EUCOMM)Wtsi>/Dmxl2<+>,Tg(Nes-cre)1Atp/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• Dmx-like 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:2444630
• transgene insertion 1, Andreas Trumpp
  http://metadb.riken.jp/db/mgi_rdf/MGI:3687337

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Dmxl2<tm1c(EUCOMM)Wtsi>/Dmxl2<+>,Tg(Nes-cre)1Atp/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Dmxl2<+>|Dmxl2<tm1c(EUCOMM)Wtsi>|Tg(Nes-cre)1Atp

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6N * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal hypothalamus morphology
  http://purl.obolibrary.org/obo/MP_0000837

文献

http://purl.org/net/cito/citesAsAuthority

• Brooke. Tata, et.al., Haploinsufficiency of Dmxl2, encoding a synaptic protein, causes infertility associated with a loss of GnRH neurons in mouse., PLoS biology, 2014, 12
  http://rdf.ncbi.nlm.nih.gov/pubmed/25248098