Purkinje cell degeneration_En1<tm2(cre)Wrst>/En1<+>,Mfn2<tm1Dcc>/Mfn2<tm3Dcc>

http://metadb.riken.jp/0000876I129129S4SvJaeSorBlackSwissEn1tm2creWrstEn1Mfn2tm1DccMfn2tm3DccMfn2tm1DccEn1En1tm2creWrstMfn2tm3Dcc

Purkinje cell degeneration_En1<tm2(cre)Wrst>/En1<+>,Mfn2<tm1Dcc>/Mfn2<tm3Dcc>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• mitofusin 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:2442230
• engrailed 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:95389

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• En1<tm2(cre)Wrst>/En1<+>,Mfn2<tm1Dcc>/Mfn2<tm3Dcc>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Mfn2<tm1Dcc>|En1<+>|En1<tm2(cre)Wrst>|Mfn2<tm3Dcc>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * 129S4/SvJaeSor * Black Swiss

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• Purkinje cell degeneration
  http://purl.obolibrary.org/obo/MP_0000876

文献

http://purl.org/net/cito/citesAsAuthority

• Hsiuchen. Chen, et.al., Mitochondrial fusion protects against neurodegeneration in the cerebellum., Cell, 2007, 130
  http://rdf.ncbi.nlm.nih.gov/pubmed/17693261