Purkinje cell degeneration_Prnp<tm1Cwe>/Prnp<tm1Cwe>,Tg(Prnp-tTA)F959Sbp/0,Tg(tetO-ATXN3)2904Olri/Tg(tetO-ATXN3)2904Olri

http://metadb.riken.jp/0000876I129S7SvEvBrdC57BL6FVBPrnptm1CwePrnptm1CweTgPrnptTAF959Sbp0TgtetOATXN32904OlriTgtetOATXN32904OlriTgtetOATXN32904OlriPrnptm1CweTgPrnptTAF959Sbp

Purkinje cell degeneration_Prnp<tm1Cwe>/Prnp<tm1Cwe>,Tg(Prnp-tTA)F959Sbp/0,Tg(tetO-ATXN3)2904Olri/Tg(tetO-ATXN3)2904Olri

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• prion protein
  http://metadb.riken.jp/db/mgi_rdf/MGI:97769
• transgene insertion 2904, Olaf Riess
  http://metadb.riken.jp/db/mgi_rdf/MGI:4410557
• transgene insertion F959, Stanley B Prusiner
  http://metadb.riken.jp/db/mgi_rdf/MGI:2651601

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Prnp<tm1Cwe>/Prnp<tm1Cwe>,Tg(Prnp-tTA)F959Sbp/0,Tg(tetO-ATXN3)2904Olri/Tg(tetO-ATXN3)2904Olri

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(tetO-ATXN3)2904Olri|Prnp<tm1Cwe>|Tg(Prnp-tTA)F959Sbp

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S7/SvEvBrd * C57BL/6 * FVB

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• Purkinje cell degeneration
  http://purl.obolibrary.org/obo/MP_0000876

文献

http://purl.org/net/cito/citesAsAuthority

• Jana. Boy, et.al., Reversibility of symptoms in a conditional mouse model of spinocerebellar ataxia type 3., Human molecular genetics, 2009, 18
  http://rdf.ncbi.nlm.nih.gov/pubmed/19666958