abnormal midbrain morphology_En1<tm7(cre/ESR1)Alj>/0,Fgf8<tm1.3Mrt>/Fgf8<tm1.4Mrt>

http://metadb.riken.jp/0000897I129P2OlaHsd129S6SvEvTacEn1tm7creESR1Alj0Fgf8tm13MrtFgf8tm14MrtFgf8tm13MrtEn1tm7creESR1AljFgf8tm14Mrt

abnormal midbrain morphology_En1<tm7(cre/ESR1)Alj>/0,Fgf8<tm1.3Mrt>/Fgf8<tm1.4Mrt>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• fibroblast growth factor 8
  http://metadb.riken.jp/db/mgi_rdf/MGI:99604
• engrailed 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:95389

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• En1<tm7(cre/ESR1)Alj>/0,Fgf8<tm1.3Mrt>/Fgf8<tm1.4Mrt>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Fgf8<tm1.3Mrt>|En1<tm7(cre/ESR1)Alj>|Fgf8<tm1.4Mrt>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S6/SvEvTac

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal midbrain morphology
  http://purl.obolibrary.org/obo/MP_0000897

文献

http://purl.org/net/cito/citesAsAuthority

• Qiuxia. Guo, et.al., Fgf8b-containing spliceforms, but not Fgf8a, are essential for Fgf8 function during development of the midbrain and cerebellum., Developmental biology, 2010, 338
  http://rdf.ncbi.nlm.nih.gov/pubmed/19968985