Qiuxia. Guo, et.al., Fgf8b-containing spliceforms, but not Fgf8a, are essential for Fgf8 function during development of the midbrain and cerebellum., Developmental biology, 2010, 338

http://rdf.ncbi.nlm.nih.gov/pubmed/19968985

Qiuxia. Guo, et.al., Fgf8b-containing spliceforms, but not Fgf8a, are essential for Fgf8 function during development of the midbrain and cerebellum., Developmental biology, 2010, 338

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Fgf8<tm2.1Jyhl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4437219

class

http://purl.org/net/cito/citesAsAuthority

• Fgf8<tm2.1Jyhl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4437219

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal rhombomere morphology_En1<tm7(cre/ESR1)Alj>/0,Fgf8<tm1.1Jyhl>/Fgf8<tm1.3Mrt>
  http://metadb.riken.jp/0000933I129P2OlaHsd129S6SvEvTacEn1tm7creESR1Alj0Fgf8tm11JyhlFgf8tm13MrtFgf8tm11JyhlFgf8tm13MrtEn1tm7creESR1Alj
• decreased dopaminergic neuron number_En1<tm7(cre/ESR1)Alj>/0,Fgf8<tm1.1Jyhl>/Fgf8<tm1.3Mrt>
  http://metadb.riken.jp/0011448I129P2OlaHsd129S6SvEvTacEn1tm7creESR1Alj0Fgf8tm11JyhlFgf8tm13MrtFgf8tm11JyhlFgf8tm13MrtEn1tm7creESR1Alj
• perinatal lethality, complete penetrance_En1<tm7(cre/ESR1)Alj>/0,Fgf8<tm1.1Jyhl>/Fgf8<tm1.3Mrt>
  http://metadb.riken.jp/0011089I129P2OlaHsd129S6SvEvTacEn1tm7creESR1Alj0Fgf8tm11JyhlFgf8tm13MrtFgf8tm11JyhlFgf8tm13MrtEn1tm7creESR1Alj
• abnormal Raphe nucleus morphology_En1<tm7(cre/ESR1)Alj>/0,Fgf8<tm1.1Jyhl>/Fgf8<tm1.3Mrt>
  http://metadb.riken.jp/0004861I129P2OlaHsd129S6SvEvTacEn1tm7creESR1Alj0Fgf8tm11JyhlFgf8tm13MrtFgf8tm11JyhlFgf8tm13MrtEn1tm7creESR1Alj
• decreased body weight_Fgf8<tm2.1Jyhl>/Fgf8<tm2.1Jyhl>
  http://metadb.riken.jp/0001262I129S6SvEvTacCD1Fgf8tm21JyhlFgf8tm21JyhlFgf8tm21Jyhl
• postnatal lethality, incomplete penetrance_Fgf8<tm2.1Jyhl>/Fgf8<tm2.1Jyhl>
  http://metadb.riken.jp/0011086B6129S6Fgf8tm21JyhlFgf8tm21JyhlFgf8tm21JyhlFgf8tm21Jyhl
• abnormal cerebellum anterior vermis morphology_Fgf17<tm1Dor>/Fgf17<tm1Dor>
  http://metadb.riken.jp/0000867I129S6SvEvTacFgf17tm1DorFgf17tm1DorFgf17tm1Dor
• abnormal neural tube morphology_En1<tm7(cre/ESR1)Alj>/0,Fgf8<tm1.1Jyhl>/Fgf8<tm1.3Mrt>
  http://metadb.riken.jp/0002151I129P2OlaHsd129S6SvEvTacEn1tm7creESR1Alj0Fgf8tm11JyhlFgf8tm13MrtFgf8tm11JyhlFgf8tm13MrtEn1tm7creESR1Alj
• abnormal Raphe nucleus morphology_En1<tm7(cre/ESR1)Alj>/0,Fgf8<tm1.3Mrt>/Fgf8<tm1.4Mrt>
  http://metadb.riken.jp/0004861I129P2OlaHsd129S6SvEvTacEn1tm7creESR1Alj0Fgf8tm13MrtFgf8tm14MrtFgf8tm13MrtEn1tm7creESR1AljFgf8tm14Mrt
• decreased dopaminergic neuron number_En1<tm7(cre/ESR1)Alj>/0,Fgf8<tm1.3Mrt>/Fgf8<tm1.4Mrt>
  http://metadb.riken.jp/0011448I129P2OlaHsd129S6SvEvTacEn1tm7creESR1Alj0Fgf8tm13MrtFgf8tm14MrtFgf8tm13MrtEn1tm7creESR1AljFgf8tm14Mrt
• abnormal substantia nigra morphology_En1<tm7(cre/ESR1)Alj>/0,Fgf8<tm1.3Mrt>/Fgf8<tm1.4Mrt>
  http://metadb.riken.jp/0000836I129P2OlaHsd129S6SvEvTacEn1tm7creESR1Alj0Fgf8tm13MrtFgf8tm14MrtFgf8tm13MrtEn1tm7creESR1AljFgf8tm14Mrt
• small cerebellum_En1<tm7(cre/ESR1)Alj>/0,Fgf8<tm1.1Jyhl>/Fgf8<tm1.3Mrt>
  http://metadb.riken.jp/0000852I129P2OlaHsd129S6SvEvTacEn1tm7creESR1Alj0Fgf8tm11JyhlFgf8tm13MrtFgf8tm11JyhlFgf8tm13MrtEn1tm7creESR1Alj
• abnormal serotonergic neuron morphology_En1<tm7(cre/ESR1)Alj>/0,Fgf8<tm1.3Mrt>/Fgf8<tm1.4Mrt>
  http://metadb.riken.jp/0003877I129P2OlaHsd129S6SvEvTacEn1tm7creESR1Alj0Fgf8tm13MrtFgf8tm14MrtFgf8tm13MrtEn1tm7creESR1AljFgf8tm14Mrt
• decreased body weight_Fgf8<tm2.1Jyhl>/Fgf8<+>
  http://metadb.riken.jp/0001262B6129S6Fgf8tm21JyhlFgf8tm21JyhlFgf8Fgf8tm21JyhlFgf8
• abnormal midbrain morphology_En1<tm7(cre/ESR1)Alj>/0,Fgf8<tm1.3Mrt>/Fgf8<tm1.4Mrt>
  http://metadb.riken.jp/0000897I129P2OlaHsd129S6SvEvTacEn1tm7creESR1Alj0Fgf8tm13MrtFgf8tm14MrtFgf8tm13MrtEn1tm7creESR1AljFgf8tm14Mrt
• decreased inferior colliculus size_Fgf17<tm1Dor>/Fgf17<tm1Dor>,Fgf8<tm1.1Jyhl>/Fgf8<tm1.1Jyhl>
  http://metadb.riken.jp/0009038I129S6SvEvTacFgf17tm1DorFgf17tm1DorFgf8tm11JyhlFgf8tm11JyhlFgf8tm11JyhlFgf17tm1Dor
• decreased inferior colliculus size_Fgf17<tm1Dor>/Fgf17<tm1Dor>
  http://metadb.riken.jp/0009038I129S6SvEvTacFgf17tm1DorFgf17tm1DorFgf17tm1Dor
• abnormal substantia nigra morphology_En1<tm7(cre/ESR1)Alj>/0,Fgf8<tm1.1Jyhl>/Fgf8<tm1.3Mrt>
  http://metadb.riken.jp/0000836I129P2OlaHsd129S6SvEvTacEn1tm7creESR1Alj0Fgf8tm11JyhlFgf8tm13MrtFgf8tm11JyhlFgf8tm13MrtEn1tm7creESR1Alj
• abnormal cerebellum anterior vermis morphology_Fgf17<tm1Dor>/Fgf17<tm1Dor>,Fgf8<tm1.1Jyhl>/Fgf8<tm1.1Jyhl>
  http://metadb.riken.jp/0000867I129S6SvEvTacFgf17tm1DorFgf17tm1DorFgf8tm11JyhlFgf8tm11JyhlFgf8tm11JyhlFgf17tm1Dor
• abnormal serotonergic neuron morphology_En1<tm7(cre/ESR1)Alj>/0,Fgf8<tm1.1Jyhl>/Fgf8<tm1.3Mrt>
  http://metadb.riken.jp/0003877I129P2OlaHsd129S6SvEvTacEn1tm7creESR1Alj0Fgf8tm11JyhlFgf8tm13MrtFgf8tm11JyhlFgf8tm13MrtEn1tm7creESR1Alj
• small cerebellum_En1<tm7(cre/ESR1)Alj>/0,Fgf8<tm1.3Mrt>/Fgf8<tm1.4Mrt>
  http://metadb.riken.jp/0000852I129P2OlaHsd129S6SvEvTacEn1tm7creESR1Alj0Fgf8tm13MrtFgf8tm14MrtFgf8tm13MrtEn1tm7creESR1AljFgf8tm14Mrt
• postnatal lethality_Fgf8<tm2.1Jyhl>/Fgf8<tm2.1Jyhl>
  http://metadb.riken.jp/0002082I129S6SvEvTacCD1Fgf8tm21JyhlFgf8tm21JyhlFgf8tm21Jyhl
• abnormal midbrain morphology_En1<tm7(cre/ESR1)Alj>/0,Fgf8<tm1.1Jyhl>/Fgf8<tm1.3Mrt>
  http://metadb.riken.jp/0000897I129P2OlaHsd129S6SvEvTacEn1tm7creESR1Alj0Fgf8tm11JyhlFgf8tm13MrtFgf8tm11JyhlFgf8tm13MrtEn1tm7creESR1Alj