abnormal myelination_Egr2<tm2(cre)Pch>/Egr2<+>,Gt(ROSA)26Sor<tm7(Pik3ca*,EGFP)Rsky>/?

http://metadb.riken.jp/0000920I129S2SvPasC57BL6Egr2tm2crePchEgr2GtROSA26Sortm7Pik3caEGFPRskyEgr2Egr2tm2crePchGtROSA26Sortm7Pik3caEGFPRsky

abnormal myelination_Egr2<tm2(cre)Pch>/Egr2<+>,Gt(ROSA)26Sor<tm7(Pik3ca*,EGFP)Rsky>/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• early growth response 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:95296
• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Egr2<tm2(cre)Pch>/Egr2<+>,Gt(ROSA)26Sor<tm7(Pik3ca*,EGFP)Rsky>/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Egr2<+>|Egr2<tm2(cre)Pch>|Gt(ROSA)26Sor<tm7(Pik3ca*,EGFP)Rsky>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal myelination
  http://purl.obolibrary.org/obo/MP_0000920

文献

http://purl.org/net/cito/citesAsAuthority

• Maria E. Sheean, et.al., Activation of MAPK overrides the termination of myelin growth and replaces Nrg1/ErbB3 signals during Schwann cell development and myelination., Genes & development, 2014, 28
  http://rdf.ncbi.nlm.nih.gov/pubmed/24493648