motor neuron degeneration_Tg(Prnp-FUS)WT3Cshw/Tg(Prnp-FUS)WT3Cshw

http://metadb.riken.jp/0000938IC57BL6CrlCD1ICRTgPrnpFUSWT3CshwTgPrnpFUSWT3CshwTgPrnpFUSWT3Cshw

motor neuron degeneration_Tg(Prnp-FUS)WT3Cshw/Tg(Prnp-FUS)WT3Cshw

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion WT3, Christopher Shaw
  http://metadb.riken.jp/db/mgi_rdf/MGI:5445409

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(Prnp-FUS)WT3Cshw/Tg(Prnp-FUS)WT3Cshw

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Prnp-FUS)WT3Cshw

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * Crl:CD1(ICR)

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• motor neuron degeneration
  http://purl.obolibrary.org/obo/MP_0000938

文献

http://purl.org/net/cito/citesAsAuthority

• Jacqueline C. Mitchell, et.al., Overexpression of human wild-type FUS causes progressive motor neuron degeneration in an age- and dose-dependent fashion., Acta neuropathologica, 2013, 125
  http://rdf.ncbi.nlm.nih.gov/pubmed/22961620