decreased motor neuron number_Dnmt3a<tm1Jae>/Dnmt3a<tm1Jae>,Tg(Nes-cre)1Atp/0

http://metadb.riken.jp/0000939I129S4SvJaeC57BL6FVBNDnmt3atm1JaeDnmt3atm1JaeTgNescre1Atp0Dnmt3atm1JaeTgNescre1Atp

decreased motor neuron number_Dnmt3a<tm1Jae>/Dnmt3a<tm1Jae>,Tg(Nes-cre)1Atp/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• DNA methyltransferase 3A
  http://metadb.riken.jp/db/mgi_rdf/MGI:1261827
• transgene insertion 1, Andreas Trumpp
  http://metadb.riken.jp/db/mgi_rdf/MGI:3687337

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Dnmt3a<tm1Jae>/Dnmt3a<tm1Jae>,Tg(Nes-cre)1Atp/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Dnmt3a<tm1Jae>|Tg(Nes-cre)1Atp

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * C57BL/6 * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased motor neuron number
  http://purl.obolibrary.org/obo/MP_0000939

文献

http://purl.org/net/cito/citesAsAuthority

• Suzanne. Nguyen, et.al., Ablation of de novo DNA methyltransferase Dnmt3a in the nervous system leads to neuromuscular defects and shortened lifespan., Developmental dynamics : an official publication of the American Association of Anatomists, 2007, 236
  http://rdf.ncbi.nlm.nih.gov/pubmed/17477386