Suzanne. Nguyen, et.al., Ablation of de novo DNA methyltransferase Dnmt3a in the nervous system leads to neuromuscular defects and shortened lifespan., Developmental dynamics : an official publication of the American Association of Anatomists, 2007, 236

http://rdf.ncbi.nlm.nih.gov/pubmed/17477386

Suzanne. Nguyen, et.al., Ablation of de novo DNA methyltransferase Dnmt3a in the nervous system leads to neuromuscular defects and shortened lifespan., Developmental dynamics : an official publication of the American Association of Anatomists, 2007, 236

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Dnmt3a<tm1.1Jae>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3711711
• Dnmt3a<tm1Jae>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3711072

class

http://purl.org/net/cito/citesAsAuthority

• Dnmt3a<tm1.1Jae>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3711711
• Dnmt3a<tm1Jae>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3711072

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased exploration in new environment_Dnmt3a<tm1Jae>/Dnmt3a<tm1Jae>,Tg(Nes-cre)1Atp/0
  http://metadb.riken.jp/0001417I129S4SvJaeC57BL6FVBNDnmt3atm1JaeDnmt3atm1JaeTgNescre1Atp0Dnmt3atm1JaeTgNescre1Atp
• decreased motor neuron number_Dnmt3a<tm1Jae>/Dnmt3a<tm1Jae>,Tg(Nes-cre)1Atp/0
  http://metadb.riken.jp/0000939I129S4SvJaeC57BL6FVBNDnmt3atm1JaeDnmt3atm1JaeTgNescre1Atp0Dnmt3atm1JaeTgNescre1Atp
• postnatal lethality, complete penetrance_Dnmt3a<tm1.1Jae>/Dnmt3a<tm1.1Jae>
  http://metadb.riken.jp/0011085I129S4SvJaeC57BL6Dnmt3atm11JaeDnmt3atm11JaeDnmt3atm11Jae
• hypoactivity_Dnmt3a<tm1Jae>/Dnmt3a<tm1Jae>,Tg(Nes-cre)1Atp/0
  http://metadb.riken.jp/0001402I129S4SvJaeC57BL6FVBNDnmt3atm1JaeDnmt3atm1JaeTgNescre1Atp0Dnmt3atm1JaeTgNescre1Atp
• abnormal gait_Dnmt3a<tm1Jae>/Dnmt3a<tm1Jae>,Tg(Nes-cre)1Atp/0
  http://metadb.riken.jp/0001406I129S4SvJaeC57BL6FVBNDnmt3atm1JaeDnmt3atm1JaeTgNescre1Atp0Dnmt3atm1JaeTgNescre1Atp
• impaired coordination_Dnmt3a<tm1Jae>/Dnmt3a<tm1Jae>,Tg(Nes-cre)1Atp/0
  http://metadb.riken.jp/0001405I129S4SvJaeC57BL6FVBNDnmt3atm1JaeDnmt3atm1JaeTgNescre1Atp0Dnmt3atm1JaeTgNescre1Atp
• decreased body size_Dnmt3a<tm1.1Jae>/Dnmt3a<tm1.1Jae>
  http://metadb.riken.jp/0001265I129S4SvJaeC57BL6Dnmt3atm11JaeDnmt3atm11JaeDnmt3atm11Jae
• premature death_Dnmt3a<tm1Jae>/Dnmt3a<tm1Jae>,Tg(Nes-cre)1Atp/0
  http://metadb.riken.jp/0002083I129S4SvJaeC57BL6FVBNDnmt3atm1JaeDnmt3atm1JaeTgNescre1Atp0Dnmt3atm1JaeTgNescre1Atp
• decreased body weight_Dnmt3a<tm1Jae>/Dnmt3a<tm1Jae>,Tg(Nes-cre)1Atp/0
  http://metadb.riken.jp/0001262I129S4SvJaeC57BL6FVBNDnmt3atm1JaeDnmt3atm1JaeTgNescre1Atp0Dnmt3atm1JaeTgNescre1Atp
• abnormal neuromuscular synapse morphology_Dnmt3a<tm1Jae>/Dnmt3a<tm1Jae>,Tg(Nes-cre)1Atp/0
  http://metadb.riken.jp/0001053I129S4SvJaeC57BL6FVBNDnmt3atm1JaeDnmt3atm1JaeTgNescre1Atp0Dnmt3atm1JaeTgNescre1Atp
• decreased grip strength_Dnmt3a<tm1Jae>/Dnmt3a<tm1Jae>,Tg(Nes-cre)1Atp/0
  http://metadb.riken.jp/0010053I129S4SvJaeC57BL6FVBNDnmt3atm1JaeDnmt3atm1JaeTgNescre1Atp0Dnmt3atm1JaeTgNescre1Atp