abnormal enteric neuron morphology_Bax<tm1Sjk>/Bax<tm1Sjk>,Ret<tm1Heno>/Ret<tm3.1(Bcl2l1)Heno>,Tg(CAG-cre/Esr1*)5Amc/0

http://metadb.riken.jp/0001046I129X1SvJC57BL6CBABaxtm1SjkBaxtm1SjkRettm1HenoRettm31Bcl2l1HenoTgCAGcreEsr15Amc0Baxtm1SjkRettm1HenoTgCAGcreEsr15AmcRettm31Bcl2l1Heno

abnormal enteric neuron morphology_Bax<tm1Sjk>/Bax<tm1Sjk>,Ret<tm1Heno>/Ret<tm3.1(Bcl2l1)Heno>,Tg(CAG-cre/Esr1*)5Amc/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 5, Andrew P McMahon
  http://metadb.riken.jp/db/mgi_rdf/MGI:2182765
• BCL2-associated X protein
  http://metadb.riken.jp/db/mgi_rdf/MGI:99702
• ret proto-oncogene
  http://metadb.riken.jp/db/mgi_rdf/MGI:97902

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Bax<tm1Sjk>/Bax<tm1Sjk>,Ret<tm1Heno>/Ret<tm3.1(Bcl2l1)Heno>,Tg(CAG-cre/Esr1*)5Amc/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Bax<tm1Sjk>|Ret<tm1Heno>|Tg(CAG-cre/Esr1*)5Amc|Ret<tm3.1(Bcl2l1)Heno>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129X1/SvJ * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal enteric neuron morphology
  http://purl.obolibrary.org/obo/MP_0001046

文献

http://purl.org/net/cito/citesAsAuthority

• Toshihiro. Uesaka, et.al., Neural precursor death is central to the pathogenesis of intestinal aganglionosis in Ret hypomorphic mice., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010, 30
  http://rdf.ncbi.nlm.nih.gov/pubmed/20392943