Toshihiro. Uesaka, et.al., Neural precursor death is central to the pathogenesis of intestinal aganglionosis in Ret hypomorphic mice., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010, 30

http://rdf.ncbi.nlm.nih.gov/pubmed/20392943

Toshihiro. Uesaka, et.al., Neural precursor death is central to the pathogenesis of intestinal aganglionosis in Ret hypomorphic mice., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010, 30

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Ret<tm3.1(Bcl2l1)Heno>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4459031

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal feces composition_Ret<tm1Heno>/Ret<tm2(RET)Jmi>
  http://metadb.riken.jp/0003868I129X1SvJC57BL6Rettm1HenoRettm2RETJmiRettm2RETJmiRettm1Heno
• absent kidney_Ret<tm2(RET)Heno>/Ret<tm3.1(Bcl2l1)Heno>
  http://metadb.riken.jp/0000520I129SvC57BL6Rettm2RETHenoRettm31Bcl2l1HenoRettm2RETHenoRettm31Bcl2l1Heno
• abnormal defecation_Ret<tm1Heno>/Ret<tm3.1(Bcl2l1)Heno>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0003866I129X1SvJC57BL6CBARettm1HenoRettm31Bcl2l1HenoTgCAGcreEsr15Amc0TgCAGcreEsr15AmcRettm31Bcl2l1HenoRettm1Heno
• abnormal enteric neuron morphology_Ret<tm1Heno>/Ret<tm2(RET)Heno>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0001046I129X1SvJC57BL6CBARettm1HenoRettm2RETHenoTgCAGcreEsr15Amc0TgCAGcreEsr15AmcRettm1HenoRettm2RETHeno
• postnatal growth retardation_Ret<tm1Heno>/Ret<tm2(RET)Jmi>
  http://metadb.riken.jp/0001732I129X1SvJC57BL6Rettm1HenoRettm2RETJmiRettm2RETJmiRettm1Heno
• absent enteric neurons_Ret<tm1Heno>/Ret<tm2(RET)Jmi>
  http://metadb.riken.jp/0001048I129X1SvJC57BL6Rettm1HenoRettm2RETJmiRettm2RETJmiRettm1Heno
• premature death_Ret<tm1Heno>/Ret<tm2(RET)Jmi>
  http://metadb.riken.jp/0002083I129X1SvJC57BL6Rettm1HenoRettm2RETJmiRettm2RETJmiRettm1Heno
• abnormal enteric neural crest cell migration_Ret<tm2(RET)Jmi>/Ret<tm3.1(Bcl2l1)Heno>
  http://metadb.riken.jp/0013006I129SvC57BL6Rettm2RETJmiRettm31Bcl2l1HenoRettm2RETJmiRettm31Bcl2l1Heno
• abnormal enteric neural crest cell migration_Ret<tm1Heno>/Ret<tm2(RET)Jmi>
  http://metadb.riken.jp/0013006I129X1SvJC57BL6Rettm1HenoRettm2RETJmiRettm2RETJmiRettm1Heno
• postnatal lethality, incomplete penetrance_Ret<tm1Heno>/Ret<tm2(RET)Jmi>
  http://metadb.riken.jp/0011086I129X1SvJC57BL6Rettm1HenoRettm2RETJmiRettm2RETJmiRettm1Heno
• decreased body weight_Ret<tm1Heno>/Ret<tm3.1(Bcl2l1)Heno>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0001262I129X1SvJC57BL6CBARettm1HenoRettm31Bcl2l1HenoTgCAGcreEsr15Amc0TgCAGcreEsr15AmcRettm31Bcl2l1HenoRettm1Heno
• decreased body weight_Ret<tm1Heno>/Ret<tm2(RET)Jmi>
  http://metadb.riken.jp/0001262I129X1SvJC57BL6Rettm1HenoRettm2RETJmiRettm2RETJmiRettm1Heno
• abnormal enteric neuron morphology_Ret<tm1Heno>/Ret<tm3.1(Bcl2l1)Heno>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0001046I129X1SvJC57BL6CBARettm1HenoRettm31Bcl2l1HenoTgCAGcreEsr15Amc0TgCAGcreEsr15AmcRettm31Bcl2l1HenoRettm1Heno
• absent enteric neurons_Ret<tm2(RET)Jmi>/Ret<tm3.1(Bcl2l1)Heno>
  http://metadb.riken.jp/0001048I129SvC57BL6Rettm2RETJmiRettm31Bcl2l1HenoRettm2RETJmiRettm31Bcl2l1Heno
• abnormal feces composition_Ret<tm1Heno>/Ret<tm3.1(Bcl2l1)Heno>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0003868I129X1SvJC57BL6CBARettm1HenoRettm31Bcl2l1HenoTgCAGcreEsr15Amc0TgCAGcreEsr15AmcRettm31Bcl2l1HenoRettm1Heno
• absent enteric neurons_Ret<tm2(RET)Heno>/Ret<tm3.1(Bcl2l1)Heno>
  http://metadb.riken.jp/0001048I129SvC57BL6Rettm2RETHenoRettm31Bcl2l1HenoRettm2RETHenoRettm31Bcl2l1Heno
• decreased neuron apoptosis_Ret<tm3.1(Bcl2l1)Heno>/Ret<+>
  http://metadb.riken.jp/0003204I129SvC57BL6Rettm31Bcl2l1HenoRetRettm31Bcl2l1HenoRet
• abnormal enteric neuron morphology_Bax<tm1Sjk>/Bax<tm1Sjk>,Ret<tm1Heno>/Ret<tm3.1(Bcl2l1)Heno>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0001046I129X1SvJC57BL6CBABaxtm1SjkBaxtm1SjkRettm1HenoRettm31Bcl2l1HenoTgCAGcreEsr15Amc0Baxtm1SjkRettm1HenoTgCAGcreEsr15AmcRettm31Bcl2l1Heno
• abnormal defecation_Ret<tm1Heno>/Ret<tm2(RET)Jmi>
  http://metadb.riken.jp/0003866I129X1SvJC57BL6Rettm1HenoRettm2RETJmiRettm2RETJmiRettm1Heno

class

http://purl.org/net/cito/citesAsAuthority

• Ret<tm3.1(Bcl2l1)Heno>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4459031