decreased Schwann cell number_Ptpn11<tm1.1Wbm>/Ptpn11<tm1.1Wbm>,Tg(Dhh-cre)1Mejr/0

http://metadb.riken.jp/0001107I129P2OlaHsdFVBNPtpn11tm11WbmPtpn11tm11WbmTgDhhcre1Mejr0Ptpn11tm11WbmTgDhhcre1Mejr

decreased Schwann cell number_Ptpn11<tm1.1Wbm>/Ptpn11<tm1.1Wbm>,Tg(Dhh-cre)1Mejr/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• protein tyrosine phosphatase, non-receptor type 11
  http://metadb.riken.jp/db/mgi_rdf/MGI:99511
• transgene insertion 1, Dies Meijer
  http://metadb.riken.jp/db/mgi_rdf/MGI:4359596

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ptpn11<tm1.1Wbm>/Ptpn11<tm1.1Wbm>,Tg(Dhh-cre)1Mejr/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Ptpn11<tm1.1Wbm>|Tg(Dhh-cre)1Mejr

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased Schwann cell number
  http://purl.obolibrary.org/obo/MP_0001107

文献

http://purl.org/net/cito/citesAsAuthority

• Maria E. Sheean, et.al., Activation of MAPK overrides the termination of myelin growth and replaces Nrg1/ErbB3 signals during Schwann cell development and myelination., Genes & development, 2014, 28
  http://rdf.ncbi.nlm.nih.gov/pubmed/24493648