abnormal ovary morphology_Pik3ca<tm1.1Waph>/Pik3ca<+>,Pten<tm1Hwu>/Pten<tm1Hwu>

http://metadb.riken.jp/0001126I129S1Sv129S4SvJaeBALBcC57BL6Pik3catm11WaphPik3caPtentm1HwuPtentm1HwuPtentm1HwuPik3catm11WaphPik3ca

abnormal ovary morphology_Pik3ca<tm1.1Waph>/Pik3ca<+>,Pten<tm1Hwu>/Pten<tm1Hwu>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
  http://metadb.riken.jp/db/mgi_rdf/MGI:1206581
• phosphatase and tensin homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:109583

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pik3ca<tm1.1Waph>/Pik3ca<+>,Pten<tm1Hwu>/Pten<tm1Hwu>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Pten<tm1Hwu>|Pik3ca<tm1.1Waph>|Pik3ca<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129S4/SvJae * BALB/c * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal ovary morphology
  http://purl.obolibrary.org/obo/MP_0001126

文献

http://purl.org/net/cito/citesAsAuthority

• Kathryn M. Kinross, et.al., An activating Pik3ca mutation coupled with Pten loss is sufficient to initiate ovarian tumorigenesis in mice., The Journal of clinical investigation, 2012, 122
  http://rdf.ncbi.nlm.nih.gov/pubmed/22214849