Kathryn M. Kinross, et.al., An activating Pik3ca mutation coupled with Pten loss is sufficient to initiate ovarian tumorigenesis in mice., The Journal of clinical investigation, 2012, 122

http://rdf.ncbi.nlm.nih.gov/pubmed/22214849

Kathryn M. Kinross, et.al., An activating Pik3ca mutation coupled with Pten loss is sufficient to initiate ovarian tumorigenesis in mice., The Journal of clinical investigation, 2012, 122

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Pik3ca<tm1.1Waph>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5427579

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• ovary hemorrhage_Pik3ca<tm1.1Waph>/Pik3ca<+>,Pten<tm1Hwu>/Pten<tm1Hwu>
  http://metadb.riken.jp/0004834I129S1Sv129S4SvJaeBALBcC57BL6Pik3catm11WaphPik3caPtentm1HwuPtentm1HwuPtentm1HwuPik3catm11WaphPik3ca
• hemorrhagic ascites_Pik3ca<tm1.1Waph>/Pik3ca<+>,Pten<tm1Hwu>/Pten<tm1Hwu>
  http://metadb.riken.jp/0013184I129S1Sv129S4SvJaeBALBcC57BL6Pik3catm11WaphPik3caPtentm1HwuPtentm1HwuPtentm1HwuPik3catm11WaphPik3ca
• premature death_Pik3ca<tm1.1Waph>/Pik3ca<+>,Pten<tm1Hwu>/Pten<tm1Hwu>
  http://metadb.riken.jp/0002083I129S1Sv129S4SvJaeBALBcC57BL6Pik3catm11WaphPik3caPtentm1HwuPtentm1HwuPtentm1HwuPik3catm11WaphPik3ca
• abnormal ovary physiology_Pik3ca<tm1.1Waph>/Pik3ca<+>,Pten<tm1Hwu>/Pten<tm1Hwu>
  http://metadb.riken.jp/0003507I129S1Sv129S4SvJaeBALBcC57BL6Pik3catm11WaphPik3caPtentm1HwuPtentm1HwuPtentm1HwuPik3catm11WaphPik3ca
• increased adenocarcinoma incidence_Pik3ca<tm1.1Waph>/Pik3ca<+>,Pten<tm1Hwu>/Pten<tm1Hwu>
  http://metadb.riken.jp/0009308I129S1Sv129S4SvJaeBALBcC57BL6Pik3catm11WaphPik3caPtentm1HwuPtentm1HwuPtentm1HwuPik3catm11WaphPik3ca
• abnormal diaphragm morphology_Pik3ca<tm1.1Waph>/Pik3ca<+>,Pten<tm1Hwu>/Pten<tm1Hwu>
  http://metadb.riken.jp/0002279I129S1Sv129S4SvJaeBALBcC57BL6Pik3catm11WaphPik3caPtentm1HwuPtentm1HwuPtentm1HwuPik3catm11WaphPik3ca
• increased granulosa cell tumor incidence_Pik3ca<tm1.1Waph>/Pik3ca<+>,Pten<tm1Hwu>/Pten<tm1Hwu>
  http://metadb.riken.jp/0012411I129S1Sv129S4SvJaeBALBcC57BL6Pik3catm11WaphPik3caPtentm1HwuPtentm1HwuPtentm1HwuPik3catm11WaphPik3ca
• abnormal ovary morphology_Pik3ca<tm1.1Waph>/Pik3ca<+>,Pten<tm1Hwu>/Pten<tm1Hwu>
  http://metadb.riken.jp/0001126I129S1Sv129S4SvJaeBALBcC57BL6Pik3catm11WaphPik3caPtentm1HwuPtentm1HwuPtentm1HwuPik3catm11WaphPik3ca
• increased ovary tumor incidence_Pik3ca<tm1.1Waph>/Pik3ca<+>,Pten<tm1Hwu>/Pten<tm1Hwu>
  http://metadb.riken.jp/0008000I129S1Sv129S4SvJaeBALBcC57BL6Pik3catm11WaphPik3caPtentm1HwuPtentm1HwuPtentm1HwuPik3catm11WaphPik3ca
• abnormal peritoneum morphology_Pik3ca<tm1.1Waph>/Pik3ca<+>,Pten<tm1Hwu>/Pten<tm1Hwu>
  http://metadb.riken.jp/0009216I129S1Sv129S4SvJaeBALBcC57BL6Pik3catm11WaphPik3caPtentm1HwuPtentm1HwuPtentm1HwuPik3catm11WaphPik3ca
• abnormal ovary morphology_Pik3ca<tm1.1Waph>/Pik3ca<+>
  http://metadb.riken.jp/0001126I129S1SvC57BL6Pik3catm11WaphPik3caPik3caPik3catm11Waph
• decreased fibroblast apoptosis_Pik3ca<tm1.1Waph>/Pik3ca<+>
  http://metadb.riken.jp/0013502I129S1SvC57BL6Pik3catm11WaphPik3caPik3caPik3catm11Waph
• increased fibroblast proliferation_Pik3ca<tm1.1Waph>/Pik3ca<+>
  http://metadb.riken.jp/0011703I129S1SvC57BL6Pik3catm11WaphPik3caPik3caPik3catm11Waph

class

http://purl.org/net/cito/citesAsAuthority

• Pik3ca<tm1.1Waph>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5427579