abnormal lung development_Kras<tm1Bbd>/Kras<+>,Mapk14<tm1Nbr>/Mapk14<tm2Nbr>,Polr2a<tm1(cre/ERT2)Bbd>/Polr2a<+>

http://metadb.riken.jp/0001176I129S1Sv129X1SvJC57BL6CD1SJLKrastm1BbdKrasMapk14tm1NbrMapk14tm2NbrPolr2atm1creERT2BbdPolr2aPolr2aMapk14tm2NbrMapk14tm1NbrKrasPolr2atm1creERT2BbdKrastm1Bbd

abnormal lung development_Kras<tm1Bbd>/Kras<+>,Mapk14<tm1Nbr>/Mapk14<tm2Nbr>,Polr2a<tm1(cre/ERT2)Bbd>/Polr2a<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• mitogen-activated protein kinase 14
  http://metadb.riken.jp/db/mgi_rdf/MGI:1346865
• Kirsten rat sarcoma viral oncogene homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:96680
• polymerase (RNA) II (DNA directed) polypeptide A
  http://metadb.riken.jp/db/mgi_rdf/MGI:98086

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Kras<tm1Bbd>/Kras<+>,Mapk14<tm1Nbr>/Mapk14<tm2Nbr>,Polr2a<tm1(cre/ERT2)Bbd>/Polr2a<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Polr2a<+>|Mapk14<tm2Nbr>|Mapk14<tm1Nbr>|Kras<+>|Polr2a<tm1(cre/ERT2)Bbd>|Kras<tm1Bbd>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal lung development
  http://purl.obolibrary.org/obo/MP_0001176

文献

http://purl.org/net/cito/citesAsAuthority

• Juan José. Ventura, et.al., p38alpha MAP kinase is essential in lung stem and progenitor cell proliferation and differentiation., Nature genetics, 2007, 39
  http://rdf.ncbi.nlm.nih.gov/pubmed/17468755