Juan José. Ventura, et.al., p38alpha MAP kinase is essential in lung stem and progenitor cell proliferation and differentiation., Nature genetics, 2007, 39

http://rdf.ncbi.nlm.nih.gov/pubmed/17468755

Juan José. Ventura, et.al., p38alpha MAP kinase is essential in lung stem and progenitor cell proliferation and differentiation., Nature genetics, 2007, 39

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Mapk14<tm2Nbr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3715522

class

http://purl.org/net/cito/citesAsAuthority

• Mapk14<tm2Nbr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3715522

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased lung adenoma incidence_Kras<tm1Bbd>/Kras<+>,Mapk14<tm1Nbr>/Mapk14<tm2Nbr>,Polr2a<tm1(cre/ERT2)Bbd>/Polr2a<+>
  http://metadb.riken.jp/0002048I129S1Sv129X1SvJC57BL6CD1SJLKrastm1BbdKrasMapk14tm1NbrMapk14tm2NbrPolr2atm1creERT2BbdPolr2aPolr2aMapk14tm2NbrMapk14tm1NbrKrasPolr2atm1creERT2BbdKrastm1Bbd
• increased hemolymphoid system tumor incidence_Kras<tm1Bbd>/Kras<+>,Mapk14<tm2Nbr>/Mapk14<+>,Polr2a<tm1(cre/ERT2)Bbd>/Polr2a<+>
  http://metadb.riken.jp/0010296I129S1Sv129X1SvJC57BL6CD1SJLKrastm1BbdKrasMapk14tm2NbrMapk14Polr2atm1creERT2BbdPolr2aKrastm1BbdPolr2atm1creERT2BbdKrasMapk14Polr2aMapk14tm2Nbr
• abnormal lung development_Kras<tm1Bbd>/Kras<+>,Mapk14<tm1Nbr>/Mapk14<tm2Nbr>,Polr2a<tm1(cre/ERT2)Bbd>/Polr2a<+>
  http://metadb.riken.jp/0001176I129S1Sv129X1SvJC57BL6CD1SJLKrastm1BbdKrasMapk14tm1NbrMapk14tm2NbrPolr2atm1creERT2BbdPolr2aPolr2aMapk14tm2NbrMapk14tm1NbrKrasPolr2atm1creERT2BbdKrastm1Bbd
• abnormal lung epithelium morphology_Mapk14<tm2Nbr>/Mapk14<tm2Nbr>,Polr2a<tm1(cre/ERT2)Bbd>/Polr2a<+>
  http://metadb.riken.jp/0006382I129C57BL6CD1SJLMapk14tm2NbrMapk14tm2NbrPolr2atm1creERT2BbdPolr2aPolr2aMapk14tm2NbrPolr2atm1creERT2Bbd
• increased lung tumor incidence_Mapk14<tm1Nbr>/Mapk14<tm2Nbr>,Polr2a<tm1(cre/ERT2)Bbd>/Polr2a<+>
  http://metadb.riken.jp/0008014I129S1Sv129X1SvJC57BL6CD1SJLMapk14tm1NbrMapk14tm2NbrPolr2atm1creERT2BbdPolr2aPolr2atm1creERT2BbdMapk14tm2NbrPolr2aMapk14tm1Nbr
• enlarged lung_Mapk14<tm1Nbr>/Mapk14<tm2Nbr>,Polr2a<tm1(cre/ERT2)Bbd>/Polr2a<+>
  http://metadb.riken.jp/0004882I129S1Sv129X1SvJC57BL6CD1SJLMapk14tm1NbrMapk14tm2NbrPolr2atm1creERT2BbdPolr2aPolr2atm1creERT2BbdMapk14tm2NbrPolr2aMapk14tm1Nbr
• abnormal lung morphology_Mapk14<tm2Nbr>/Mapk14<tm2Nbr>,Polr2a<tm1(cre/ERT2)Bbd>/Polr2a<+>
  http://metadb.riken.jp/0001175I129C57BL6CD1SJLMapk14tm2NbrMapk14tm2NbrPolr2atm1creERT2BbdPolr2aPolr2aMapk14tm2NbrPolr2atm1creERT2Bbd
• premature death_Kras<tm1Bbd>/Kras<+>,Mapk14<tm1Nbr>/Mapk14<tm2Nbr>,Polr2a<tm1(cre/ERT2)Bbd>/Polr2a<+>
  http://metadb.riken.jp/0002083I129S1Sv129X1SvJC57BL6CD1SJLKrastm1BbdKrasMapk14tm1NbrMapk14tm2NbrPolr2atm1creERT2BbdPolr2aPolr2aMapk14tm2NbrMapk14tm1NbrKrasPolr2atm1creERT2BbdKrastm1Bbd
• increased lung tumor incidence_Kras<tm1Bbd>/Kras<+>,Mapk14<tm2Nbr>/Mapk14<+>,Polr2a<tm1(cre/ERT2)Bbd>/Polr2a<+>
  http://metadb.riken.jp/0008014I129S1Sv129X1SvJC57BL6CD1SJLKrastm1BbdKrasMapk14tm2NbrMapk14Polr2atm1creERT2BbdPolr2aKrastm1BbdPolr2atm1creERT2BbdKrasMapk14Polr2aMapk14tm2Nbr
• increased lung adenoma incidence_Kras<tm1Bbd>/Kras<+>,Mapk14<tm2Nbr>/Mapk14<+>,Polr2a<tm1(cre/ERT2)Bbd>/Polr2a<+>
  http://metadb.riken.jp/0002048I129S1Sv129X1SvJC57BL6CD1SJLKrastm1BbdKrasMapk14tm2NbrMapk14Polr2atm1creERT2BbdPolr2aKrastm1BbdPolr2atm1creERT2BbdKrasMapk14Polr2aMapk14tm2Nbr
• enlarged lung_Kras<tm1Bbd>/Kras<+>,Mapk14<tm1Nbr>/Mapk14<tm2Nbr>,Polr2a<tm1(cre/ERT2)Bbd>/Polr2a<+>
  http://metadb.riken.jp/0004882I129S1Sv129X1SvJC57BL6CD1SJLKrastm1BbdKrasMapk14tm1NbrMapk14tm2NbrPolr2atm1creERT2BbdPolr2aPolr2aMapk14tm2NbrMapk14tm1NbrKrasPolr2atm1creERT2BbdKrastm1Bbd
• increased lung tumor incidence_Kras<tm1Bbd>/Kras<+>,Mapk14<tm1Nbr>/Mapk14<tm2Nbr>,Polr2a<tm1(cre/ERT2)Bbd>/Polr2a<+>
  http://metadb.riken.jp/0008014I129S1Sv129X1SvJC57BL6CD1SJLKrastm1BbdKrasMapk14tm1NbrMapk14tm2NbrPolr2atm1creERT2BbdPolr2aPolr2aMapk14tm2NbrMapk14tm1NbrKrasPolr2atm1creERT2BbdKrastm1Bbd
• abnormal lung development_Mapk14<tm1Nbr>/Mapk14<tm2Nbr>,Polr2a<tm1(cre/ERT2)Bbd>/Polr2a<+>
  http://metadb.riken.jp/0001176I129S1Sv129X1SvJC57BL6CD1SJLMapk14tm1NbrMapk14tm2NbrPolr2atm1creERT2BbdPolr2aPolr2atm1creERT2BbdMapk14tm2NbrPolr2aMapk14tm1Nbr
• increased cell proliferation_Mapk14<tm2Nbr>/Mapk14<tm2Nbr>,Polr2a<tm1(cre/ERT2)Bbd>/Polr2a<+>
  http://metadb.riken.jp/0000351I129C57BL6CD1SJLMapk14tm2NbrMapk14tm2NbrPolr2atm1creERT2BbdPolr2aPolr2aMapk14tm2NbrPolr2atm1creERT2Bbd
• abnormal pulmonary alveolus epithelial cell morphology_Mapk14<tm2Nbr>/Mapk14<tm2Nbr>,Polr2a<tm1(cre/ERT2)Bbd>/Polr2a<+>
  http://metadb.riken.jp/0002273I129C57BL6CD1SJLMapk14tm2NbrMapk14tm2NbrPolr2atm1creERT2BbdPolr2aPolr2aMapk14tm2NbrPolr2atm1creERT2Bbd
• increased lung adenocarcinoma incidence_Mapk14<tm1Nbr>/Mapk14<tm2Nbr>,Polr2a<tm1(cre/ERT2)Bbd>/Polr2a<+>
  http://metadb.riken.jp/0002027I129S1Sv129X1SvJC57BL6CD1SJLMapk14tm1NbrMapk14tm2NbrPolr2atm1creERT2BbdPolr2aPolr2atm1creERT2BbdMapk14tm2NbrPolr2aMapk14tm1Nbr
• abnormal cell cycle_Mapk14<tm2Nbr>/Mapk14<tm2Nbr>,Polr2a<tm1(cre/ERT2)Bbd>/Polr2a<+>
  http://metadb.riken.jp/0003077I129C57BL6CD1SJLMapk14tm2NbrMapk14tm2NbrPolr2atm1creERT2BbdPolr2aPolr2aMapk14tm2NbrPolr2atm1creERT2Bbd
• premature death_Mapk14<tm1Nbr>/Mapk14<tm2Nbr>,Polr2a<tm1(cre/ERT2)Bbd>/Polr2a<+>
  http://metadb.riken.jp/0002083I129S1Sv129X1SvJC57BL6CD1SJLMapk14tm1NbrMapk14tm2NbrPolr2atm1creERT2BbdPolr2aPolr2atm1creERT2BbdMapk14tm2NbrPolr2aMapk14tm1Nbr
• abnormal tumor incidence_Kras<tm1Bbd>/Kras<+>,Mapk14<tm1Nbr>/Mapk14<tm2Nbr>,Polr2a<tm1(cre/ERT2)Bbd>/Polr2a<+>
  http://metadb.riken.jp/0002019I129S1Sv129X1SvJC57BL6CD1SJLKrastm1BbdKrasMapk14tm1NbrMapk14tm2NbrPolr2atm1creERT2BbdPolr2aPolr2aMapk14tm2NbrMapk14tm1NbrKrasPolr2atm1creERT2BbdKrastm1Bbd
• increased lung adenoma incidence_Mapk14<tm1Nbr>/Mapk14<tm2Nbr>,Polr2a<tm1(cre/ERT2)Bbd>/Polr2a<+>
  http://metadb.riken.jp/0002048I129S1Sv129X1SvJC57BL6CD1SJLMapk14tm1NbrMapk14tm2NbrPolr2atm1creERT2BbdPolr2aPolr2atm1creERT2BbdMapk14tm2NbrPolr2aMapk14tm1Nbr
• abnormal tumor incidence_Mapk14<tm1Nbr>/Mapk14<tm2Nbr>,Polr2a<tm1(cre/ERT2)Bbd>/Polr2a<+>
  http://metadb.riken.jp/0002019I129S1Sv129X1SvJC57BL6CD1SJLMapk14tm1NbrMapk14tm2NbrPolr2atm1creERT2BbdPolr2aPolr2atm1creERT2BbdMapk14tm2NbrPolr2aMapk14tm1Nbr
• premature death_Kras<tm1Bbd>/Kras<+>,Mapk14<tm2Nbr>/Mapk14<+>,Polr2a<tm1(cre/ERT2)Bbd>/Polr2a<+>
  http://metadb.riken.jp/0002083I129S1Sv129X1SvJC57BL6CD1SJLKrastm1BbdKrasMapk14tm2NbrMapk14Polr2atm1creERT2BbdPolr2aKrastm1BbdPolr2atm1creERT2BbdKrasMapk14Polr2aMapk14tm2Nbr
• increased lung adenocarcinoma incidence_Kras<tm1Bbd>/Kras<+>,Mapk14<tm1Nbr>/Mapk14<tm2Nbr>,Polr2a<tm1(cre/ERT2)Bbd>/Polr2a<+>
  http://metadb.riken.jp/0002027I129S1Sv129X1SvJC57BL6CD1SJLKrastm1BbdKrasMapk14tm1NbrMapk14tm2NbrPolr2atm1creERT2BbdPolr2aPolr2aMapk14tm2NbrMapk14tm1NbrKrasPolr2atm1creERT2BbdKrastm1Bbd