thick skin_Il6<tm1Kopf>/Il6<tm1Kopf>,Junb<tm3Wag>/Junb<tm3Wag>,Tg(KRT5-cre)1Tak/0

http://metadb.riken.jp/0001200I129Sv129P2OlaHsd129S2SvPasC3HC57BL6Il6tm1KopfIl6tm1KopfJunbtm3WagJunbtm3WagTgKRT5cre1Tak0TgKRT5cre1TakJunbtm3WagIl6tm1Kopf

thick skin_Il6<tm1Kopf>/Il6<tm1Kopf>,Junb<tm3Wag>/Junb<tm3Wag>,Tg(KRT5-cre)1Tak/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• interleukin 6
  http://metadb.riken.jp/db/mgi_rdf/MGI:96559
• jun B proto-oncogene
  http://metadb.riken.jp/db/mgi_rdf/MGI:96647
• transgene insertion 1, Junji Takeda
  http://metadb.riken.jp/db/mgi_rdf/MGI:1926776

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Il6<tm1Kopf>/Il6<tm1Kopf>,Junb<tm3Wag>/Junb<tm3Wag>,Tg(KRT5-cre)1Tak/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(KRT5-cre)1Tak|Junb<tm3Wag>|Il6<tm1Kopf>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129/Sv * 129P2/OlaHsd * 129S2/SvPas * C3H * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• thick skin
  http://purl.obolibrary.org/obo/MP_0001200

文献

http://purl.org/net/cito/citesAsAuthority

• Pamina. Pflegerl, et.al., Epidermal loss of JunB leads to a SLE phenotype due to hyper IL-6 signaling., Proceedings of the National Academy of Sciences of the United States of America, 2009, 106
  http://rdf.ncbi.nlm.nih.gov/pubmed/19918056