Pamina. Pflegerl, et.al., Epidermal loss of JunB leads to a SLE phenotype due to hyper IL-6 signaling., Proceedings of the National Academy of Sciences of the United States of America, 2009, 106

http://rdf.ncbi.nlm.nih.gov/pubmed/19918056

Pamina. Pflegerl, et.al., Epidermal loss of JunB leads to a SLE phenotype due to hyper IL-6 signaling., Proceedings of the National Academy of Sciences of the United States of America, 2009, 106

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• dermatitis_Junb<tm3Wag>/Junb<tm3Wag>,Tg(KRT5-cre)1Tak/0
  http://metadb.riken.jp/0001194I129Sv129P2OlaHsdC3HC57BL6Junbtm3WagJunbtm3WagTgKRT5cre1Tak0TgKRT5cre1TakJunbtm3Wag
• thick skin_Il6<tm1Kopf>/Il6<tm1Kopf>,Junb<tm3Wag>/Junb<tm3Wag>,Tg(KRT5-cre)1Tak/0
  http://metadb.riken.jp/0001200I129Sv129P2OlaHsd129S2SvPasC3HC57BL6Il6tm1KopfIl6tm1KopfJunbtm3WagJunbtm3WagTgKRT5cre1Tak0TgKRT5cre1TakJunbtm3WagIl6tm1Kopf
• thick skin_Junb<tm3Wag>/Junb<tm3Wag>,Tg(KRT5-cre)1Tak/0
  http://metadb.riken.jp/0001200I129Sv129P2OlaHsdC3HC57BL6Junbtm3WagJunbtm3WagTgKRT5cre1Tak0TgKRT5cre1TakJunbtm3Wag
• spontaneous skin ulceration_Junb<tm3Wag>/Junb<tm3Wag>,Tg(KRT5-cre)1Tak/0
  http://metadb.riken.jp/0001209I129Sv129P2OlaHsdC3HC57BL6Junbtm3WagJunbtm3WagTgKRT5cre1Tak0TgKRT5cre1TakJunbtm3Wag
• abnormal epidermal layer morphology_Csf3<tm1Ard>/Csf3<tm1Ard>,Junb<tm3Wag>/Junb<tm3Wag>,Tg(KRT5-cre)1Tak/0
  http://metadb.riken.jp/0001216I129Sv129P2OlaHsdC3HC57BL6Csf3tm1ArdCsf3tm1ArdJunbtm3WagJunbtm3WagTgKRT5cre1Tak0Csf3tm1ArdTgKRT5cre1TakJunbtm3Wag
• hyperkeratosis_Il6<tm1Kopf>/Il6<tm1Kopf>,Junb<tm3Wag>/Junb<tm3Wag>,Tg(KRT5-cre)1Tak/0
  http://metadb.riken.jp/0001242I129Sv129P2OlaHsd129S2SvPasC3HC57BL6Il6tm1KopfIl6tm1KopfJunbtm3WagJunbtm3WagTgKRT5cre1Tak0TgKRT5cre1TakJunbtm3WagIl6tm1Kopf
他22件を見る
• increased inflammatory response_Junb<tm3Wag>/Junb<tm3Wag>,Tg(KRT5-cre)1Tak/0
  http://metadb.riken.jp/0001846I129Sv129P2OlaHsdC3HC57BL6Junbtm3WagJunbtm3WagTgKRT5cre1Tak0TgKRT5cre1TakJunbtm3Wag
• premature death_Junb<tm3Wag>/Junb<tm3Wag>,Tg(KRT5-cre)1Tak/0
  http://metadb.riken.jp/0002083I129Sv129P2OlaHsdC3HC57BL6Junbtm3WagJunbtm3WagTgKRT5cre1Tak0TgKRT5cre1TakJunbtm3Wag
• abnormal kidney morphology_Csf3<tm1Ard>/Csf3<tm1Ard>,Junb<tm3Wag>/Junb<tm3Wag>,Tg(KRT5-cre)1Tak/0
  http://metadb.riken.jp/0002135I129Sv129P2OlaHsdC3HC57BL6Csf3tm1ArdCsf3tm1ArdJunbtm3WagJunbtm3WagTgKRT5cre1Tak0Csf3tm1ArdTgKRT5cre1TakJunbtm3Wag
• increased IgE level_Junb<tm3Wag>/Junb<tm3Wag>,Tg(KRT5-cre)1Tak/0
  http://metadb.riken.jp/0002497I129Sv129P2OlaHsdC3HC57BL6Junbtm3WagJunbtm3WagTgKRT5cre1Tak0TgKRT5cre1TakJunbtm3Wag
• glomerulonephritis_Junb<tm3Wag>/Junb<tm3Wag>,Tg(KRT5-cre)1Tak/0
  http://metadb.riken.jp/0002743I129Sv129P2OlaHsdC3HC57BL6Junbtm3WagJunbtm3WagTgKRT5cre1Tak0TgKRT5cre1TakJunbtm3Wag
• albuminuria_Junb<tm3Wag>/Junb<tm3Wag>,Tg(KRT5-cre)1Tak/0
  http://metadb.riken.jp/0002871I129Sv129P2OlaHsdC3HC57BL6Junbtm3WagJunbtm3WagTgKRT5cre1Tak0TgKRT5cre1TakJunbtm3Wag
• small kidney_Junb<tm3Wag>/Junb<tm3Wag>,Tg(KRT5-cre)1Tak/0
  http://metadb.riken.jp/0002989I129Sv129P2OlaHsdC3HC57BL6Junbtm3WagJunbtm3WagTgKRT5cre1Tak0TgKRT5cre1TakJunbtm3Wag
• increased anti-histone antibody level_Junb<tm3Wag>/Junb<tm3Wag>,Tg(KRT5-cre)1Tak/0
  http://metadb.riken.jp/0004796I129Sv129P2OlaHsdC3HC57BL6Junbtm3WagJunbtm3WagTgKRT5cre1Tak0TgKRT5cre1TakJunbtm3Wag
• increased susceptibility to systemic lupus erythematosus_Csf3<tm1Ard>/Csf3<tm1Ard>,Junb<tm3Wag>/Junb<tm3Wag>,Tg(KRT5-cre)1Tak/0
  http://metadb.riken.jp/0004801I129Sv129P2OlaHsdC3HC57BL6Csf3tm1ArdCsf3tm1ArdJunbtm3WagJunbtm3WagTgKRT5cre1Tak0Csf3tm1ArdTgKRT5cre1TakJunbtm3Wag
• increased susceptibility to systemic lupus erythematosus_Junb<tm3Wag>/Junb<tm3Wag>,Tg(KRT5-cre)1Tak/0
  http://metadb.riken.jp/0004801I129Sv129P2OlaHsdC3HC57BL6Junbtm3WagJunbtm3WagTgKRT5cre1Tak0TgKRT5cre1TakJunbtm3Wag
• skin inflammation_Il6<tm1Kopf>/Il6<tm1Kopf>,Junb<tm3Wag>/Junb<tm3Wag>,Tg(KRT5-cre)1Tak/0
  http://metadb.riken.jp/0004947I129Sv129P2OlaHsd129S2SvPasC3HC57BL6Il6tm1KopfIl6tm1KopfJunbtm3WagJunbtm3WagTgKRT5cre1Tak0TgKRT5cre1TakJunbtm3WagIl6tm1Kopf
• kidney atrophy_Junb<tm3Wag>/Junb<tm3Wag>,Tg(KRT5-cre)1Tak/0
  http://metadb.riken.jp/0004970I129Sv129P2OlaHsdC3HC57BL6Junbtm3WagJunbtm3WagTgKRT5cre1Tak0TgKRT5cre1TakJunbtm3Wag
• increased plasma cell number_Junb<tm3Wag>/Junb<tm3Wag>,Tg(KRT5-cre)1Tak/0
  http://metadb.riken.jp/0008097I129Sv129P2OlaHsdC3HC57BL6Junbtm3WagJunbtm3WagTgKRT5cre1Tak0TgKRT5cre1TakJunbtm3Wag
• podocyte foot process effacement_Junb<tm3Wag>/Junb<tm3Wag>,Tg(KRT5-cre)1Tak/0
  http://metadb.riken.jp/0008140I129Sv129P2OlaHsdC3HC57BL6Junbtm3WagJunbtm3WagTgKRT5cre1Tak0TgKRT5cre1TakJunbtm3Wag
• increased circulating interleukin-6 level_Junb<tm3Wag>/Junb<tm3Wag>,Tg(KRT5-cre)1Tak/0
  http://metadb.riken.jp/0008596I129Sv129P2OlaHsdC3HC57BL6Junbtm3WagJunbtm3WagTgKRT5cre1Tak0TgKRT5cre1TakJunbtm3Wag
• increased interleukin-6 secretion_Junb<tm3Wag>/Junb<tm3Wag>,Tg(KRT5-cre)1Tak/0
  http://metadb.riken.jp/0008705I129Sv129P2OlaHsdC3HC57BL6Junbtm3WagJunbtm3WagTgKRT5cre1Tak0TgKRT5cre1TakJunbtm3Wag
• abnormal epidermal-dermal junction morphology_Junb<tm3Wag>/Junb<tm3Wag>,Tg(KRT5-cre)1Tak/0
  http://metadb.riken.jp/0011159I129Sv129P2OlaHsdC3HC57BL6Junbtm3WagJunbtm3WagTgKRT5cre1Tak0TgKRT5cre1TakJunbtm3Wag
• abnormal glomerular capillary morphology_Junb<tm3Wag>/Junb<tm3Wag>,Tg(KRT5-cre)1Tak/0
  http://metadb.riken.jp/0011320I129Sv129P2OlaHsdC3HC57BL6Junbtm3WagJunbtm3WagTgKRT5cre1Tak0TgKRT5cre1TakJunbtm3Wag
• tubulointerstitial nephritis_Junb<tm3Wag>/Junb<tm3Wag>,Tg(KRT5-cre)1Tak/0
  http://metadb.riken.jp/0011405I129Sv129P2OlaHsdC3HC57BL6Junbtm3WagJunbtm3WagTgKRT5cre1Tak0TgKRT5cre1TakJunbtm3Wag
• increased renal glomerulus basement membrane thickness_Junb<tm3Wag>/Junb<tm3Wag>,Tg(KRT5-cre)1Tak/0
  http://metadb.riken.jp/0011409I129Sv129P2OlaHsdC3HC57BL6Junbtm3WagJunbtm3WagTgKRT5cre1Tak0TgKRT5cre1TakJunbtm3Wag
• mesangial cell hyperplasia_Junb<tm3Wag>/Junb<tm3Wag>,Tg(KRT5-cre)1Tak/0
  http://metadb.riken.jp/0011427I129Sv129P2OlaHsdC3HC57BL6Junbtm3WagJunbtm3WagTgKRT5cre1Tak0TgKRT5cre1TakJunbtm3Wag
• increased renal glomerulus lobularity_Junb<tm3Wag>/Junb<tm3Wag>,Tg(KRT5-cre)1Tak/0
  http://metadb.riken.jp/0011567I129Sv129P2OlaHsdC3HC57BL6Junbtm3WagJunbtm3WagTgKRT5cre1Tak0TgKRT5cre1TakJunbtm3Wag