skin hypoplasia_Map2k1<tm1Chrn>/Map2k1<tm1Chrn>,Map2k2<tm1Chrn>/Map2k2<tm1Chrn>,Tg(KRT14-cre/ERT2)1Ipc/?

http://metadb.riken.jp/0001215I129SvC57BL6JSJLMap2k1tm1ChrnMap2k1tm1ChrnMap2k2tm1ChrnMap2k2tm1ChrnTgKRT14creERT21IpcTgKRT14creERT21IpcMap2k1tm1ChrnMap2k2tm1Chrn

skin hypoplasia_Map2k1<tm1Chrn>/Map2k1<tm1Chrn>,Map2k2<tm1Chrn>/Map2k2<tm1Chrn>,Tg(KRT14-cre/ERT2)1Ipc/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, I Pierre Chambon
  http://metadb.riken.jp/db/mgi_rdf/MGI:2177423
• mitogen-activated protein kinase kinase 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1346866
• mitogen-activated protein kinase kinase 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:1346867

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Map2k1<tm1Chrn>/Map2k1<tm1Chrn>,Map2k2<tm1Chrn>/Map2k2<tm1Chrn>,Tg(KRT14-cre/ERT2)1Ipc/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(KRT14-cre/ERT2)1Ipc|Map2k1<tm1Chrn>|Map2k2<tm1Chrn>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129/Sv * C57BL/6J * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• skin hypoplasia
  http://purl.obolibrary.org/obo/MP_0001215

文献

http://purl.org/net/cito/citesAsAuthority

• Florence A. Scholl, et.al., Mek1/2 MAPK kinases are essential for Mammalian development, homeostasis, and Raf-induced hyperplasia., Developmental cell, 2007, 12
  http://rdf.ncbi.nlm.nih.gov/pubmed/17419998