abnormal dermal layer morphology_Gt(ROSA)26Sor<tm1(Tgfbr1*)Crm>/Gt(ROSA)26Sor<+>,Tg(Col1a2-cre/ERT,-ALPP)7Cpd/0

http://metadb.riken.jp/0001243I129S7SvEvBrdC57BL6DBA2GtROSA26Sortm1Tgfbr1CrmGtROSA26SorTgCol1a2creERTALPP7Cpd0GtROSA26Sortm1Tgfbr1CrmTgCol1a2creERTALPP7CpdGtROSA26Sor

abnormal dermal layer morphology_Gt(ROSA)26Sor<tm1(Tgfbr1*)Crm>/Gt(ROSA)26Sor<+>,Tg(Col1a2-cre/ERT,-ALPP)7Cpd/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735
• transgene insertion 7, Christopher P Denton
  http://metadb.riken.jp/db/mgi_rdf/MGI:3785759

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gt(ROSA)26Sor<tm1(Tgfbr1*)Crm>/Gt(ROSA)26Sor<+>,Tg(Col1a2-cre/ERT,-ALPP)7Cpd/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gt(ROSA)26Sor<tm1(Tgfbr1*)Crm>|Tg(Col1a2-cre/ERT,-ALPP)7Cpd|Gt(ROSA)26Sor<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S7/SvEvBrd * C57BL/6 * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal dermal layer morphology
  http://purl.obolibrary.org/obo/MP_0001243

文献

http://purl.org/net/cito/citesAsAuthority

• Sonali. Sonnylal, et.al., Postnatal induction of transforming growth factor beta signaling in fibroblasts of mice recapitulates clinical, histologic, and biochemical features of scleroderma., Arthritis and rheumatism, 2007, 56
  http://rdf.ncbi.nlm.nih.gov/pubmed/17195237