Sonali. Sonnylal, et.al., Postnatal induction of transforming growth factor beta signaling in fibroblasts of mice recapitulates clinical, histologic, and biochemical features of scleroderma., Arthritis and rheumatism, 2007, 56

http://rdf.ncbi.nlm.nih.gov/pubmed/17195237

Sonali. Sonnylal, et.al., Postnatal induction of transforming growth factor beta signaling in fibroblasts of mice recapitulates clinical, histologic, and biochemical features of scleroderma., Arthritis and rheumatism, 2007, 56

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Gt(ROSA)26Sor<tm1(Tgfbr1*)Crm>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3785744

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal skin condition_Gt(ROSA)26Sor<tm1(Tgfbr1*)Crm>/Gt(ROSA)26Sor<+>,Tg(Col1a2-cre/ERT,-ALPP)7Cpd/0
  http://metadb.riken.jp/0001191I129S7SvEvBrdC57BL6DBA2GtROSA26Sortm1Tgfbr1CrmGtROSA26SorTgCol1a2creERTALPP7Cpd0GtROSA26Sortm1Tgfbr1CrmTgCol1a2creERTALPP7CpdGtROSA26Sor
• thick dermal layer_Gt(ROSA)26Sor<tm1(Tgfbr1*)Crm>/Gt(ROSA)26Sor<+>,Tg(Col1a2-cre/ERT,-ALPP)7Cpd/0
  http://metadb.riken.jp/0001245I129S7SvEvBrdC57BL6DBA2GtROSA26Sortm1Tgfbr1CrmGtROSA26SorTgCol1a2creERTALPP7Cpd0GtROSA26Sortm1Tgfbr1CrmTgCol1a2creERTALPP7CpdGtROSA26Sor
• abnormal kidney arterial blood vessel morphology_Gt(ROSA)26Sor<tm1(Tgfbr1*)Crm>/Gt(ROSA)26Sor<+>,Tg(Col1a2-cre/ERT,-ALPP)7Cpd/0
  http://metadb.riken.jp/0011309I129S7SvEvBrdC57BL6DBA2GtROSA26Sortm1Tgfbr1CrmGtROSA26SorTgCol1a2creERTALPP7Cpd0GtROSA26Sortm1Tgfbr1CrmTgCol1a2creERTALPP7CpdGtROSA26Sor
• abnormal blood vessel morphology_Gt(ROSA)26Sor<tm1(Tgfbr1*)Crm>/Gt(ROSA)26Sor<+>,Tg(Col1a2-cre/ERT,-ALPP)7Cpd/0
  http://metadb.riken.jp/0001614I129S7SvEvBrdC57BL6DBA2GtROSA26Sortm1Tgfbr1CrmGtROSA26SorTgCol1a2creERTALPP7Cpd0GtROSA26Sortm1Tgfbr1CrmTgCol1a2creERTALPP7CpdGtROSA26Sor
• vascular smooth muscle hypertrophy_Gt(ROSA)26Sor<tm1(Tgfbr1*)Crm>/Gt(ROSA)26Sor<+>,Tg(Col1a2-cre/ERT,-ALPP)7Cpd/0
  http://metadb.riken.jp/0002975I129S7SvEvBrdC57BL6DBA2GtROSA26Sortm1Tgfbr1CrmGtROSA26SorTgCol1a2creERTALPP7Cpd0GtROSA26Sortm1Tgfbr1CrmTgCol1a2creERTALPP7CpdGtROSA26Sor
• thick skin_Gt(ROSA)26Sor<tm1(Tgfbr1*)Crm>/Gt(ROSA)26Sor<+>,Tg(Col1a2-cre/ERT,-ALPP)7Cpd/0
  http://metadb.riken.jp/0001200I129S7SvEvBrdC57BL6DBA2GtROSA26Sortm1Tgfbr1CrmGtROSA26SorTgCol1a2creERTALPP7Cpd0GtROSA26Sortm1Tgfbr1CrmTgCol1a2creERTALPP7CpdGtROSA26Sor
• abnormal blood vessel physiology_Gt(ROSA)26Sor<tm1(Tgfbr1*)Crm>/Gt(ROSA)26Sor<+>,Tg(Col1a2-cre/ERT,-ALPP)7Cpd/0
  http://metadb.riken.jp/0000249I129S7SvEvBrdC57BL6DBA2GtROSA26Sortm1Tgfbr1CrmGtROSA26SorTgCol1a2creERTALPP7Cpd0GtROSA26Sortm1Tgfbr1CrmTgCol1a2creERTALPP7CpdGtROSA26Sor
• sparse hair_Gt(ROSA)26Sor<tm1(Tgfbr1*)Crm>/Gt(ROSA)26Sor<+>,Tg(Col1a2-cre/ERT,-ALPP)7Cpd/0
  http://metadb.riken.jp/0000416I129S7SvEvBrdC57BL6DBA2GtROSA26Sortm1Tgfbr1CrmGtROSA26SorTgCol1a2creERTALPP7Cpd0GtROSA26Sortm1Tgfbr1CrmTgCol1a2creERTALPP7CpdGtROSA26Sor
• thin epidermis_Gt(ROSA)26Sor<tm1(Tgfbr1*)Crm>/Gt(ROSA)26Sor<+>,Tg(Col1a2-cre/ERT,-ALPP)7Cpd/0
  http://metadb.riken.jp/0001218I129S7SvEvBrdC57BL6DBA2GtROSA26Sortm1Tgfbr1CrmGtROSA26SorTgCol1a2creERTALPP7Cpd0GtROSA26Sortm1Tgfbr1CrmTgCol1a2creERTALPP7CpdGtROSA26Sor
• decreased body weight_Gt(ROSA)26Sor<tm1(Tgfbr1*)Crm>/Gt(ROSA)26Sor<+>,Tg(Col1a2-cre/ERT,-ALPP)7Cpd/0
  http://metadb.riken.jp/0001262I129S7SvEvBrdC57BL6DBA2GtROSA26Sortm1Tgfbr1CrmGtROSA26SorTgCol1a2creERTALPP7Cpd0GtROSA26Sortm1Tgfbr1CrmTgCol1a2creERTALPP7CpdGtROSA26Sor
• abnormal lung vasculature morphology_Gt(ROSA)26Sor<tm1(Tgfbr1*)Crm>/Gt(ROSA)26Sor<+>,Tg(Col1a2-cre/ERT,-ALPP)7Cpd/0
  http://metadb.riken.jp/0004007I129S7SvEvBrdC57BL6DBA2GtROSA26Sortm1Tgfbr1CrmGtROSA26SorTgCol1a2creERTALPP7Cpd0GtROSA26Sortm1Tgfbr1CrmTgCol1a2creERTALPP7CpdGtROSA26Sor
• abnormal dermal layer morphology_Gt(ROSA)26Sor<tm1(Tgfbr1*)Crm>/Gt(ROSA)26Sor<+>,Tg(Col1a2-cre/ERT,-ALPP)7Cpd/0
  http://metadb.riken.jp/0001243I129S7SvEvBrdC57BL6DBA2GtROSA26Sortm1Tgfbr1CrmGtROSA26SorTgCol1a2creERTALPP7Cpd0GtROSA26Sortm1Tgfbr1CrmTgCol1a2creERTALPP7CpdGtROSA26Sor
• decreased subcutaneous adipose tissue amount_Gt(ROSA)26Sor<tm1(Tgfbr1*)Crm>/Gt(ROSA)26Sor<+>,Tg(Col1a2-cre/ERT,-ALPP)7Cpd/0
  http://metadb.riken.jp/0008844I129S7SvEvBrdC57BL6DBA2GtROSA26Sortm1Tgfbr1CrmGtROSA26SorTgCol1a2creERTALPP7Cpd0GtROSA26Sortm1Tgfbr1CrmTgCol1a2creERTALPP7CpdGtROSA26Sor
• abnormal artery morphology_Gt(ROSA)26Sor<tm1(Tgfbr1*)Crm>/Gt(ROSA)26Sor<+>,Tg(Col1a2-cre/ERT,-ALPP)7Cpd/0
  http://metadb.riken.jp/0002191I129S7SvEvBrdC57BL6DBA2GtROSA26Sortm1Tgfbr1CrmGtROSA26SorTgCol1a2creERTALPP7Cpd0GtROSA26Sortm1Tgfbr1CrmTgCol1a2creERTALPP7CpdGtROSA26Sor
• renal interstitial fibrosis_Gt(ROSA)26Sor<tm1(Tgfbr1*)Crm>/Gt(ROSA)26Sor<+>,Tg(Col1a2-cre/ERT,-ALPP)7Cpd/0
  http://metadb.riken.jp/0003215I129S7SvEvBrdC57BL6DBA2GtROSA26Sortm1Tgfbr1CrmGtROSA26SorTgCol1a2creERTALPP7Cpd0GtROSA26Sortm1Tgfbr1CrmTgCol1a2creERTALPP7CpdGtROSA26Sor

class

http://purl.org/net/cito/citesAsAuthority

• Gt(ROSA)26Sor<tm1(Tgfbr1*)Crm>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3785744