abnormal dermal layer morphology_Tg(MMTV-KLF4)1Rup/0,Trp53<tm1Brd>/Trp53<+>

http://metadb.riken.jp/0001243I129S7SvEvBrdC57BL6NTacFVBNJSJLTgMMTVKLF41Rup0Trp53tm1BrdTrp53Trp53tm1BrdTrp53TgMMTVKLF41Rup

abnormal dermal layer morphology_Tg(MMTV-KLF4)1Rup/0,Trp53<tm1Brd>/Trp53<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834
• transgene insertion 1, J Michael Ruppert
  http://metadb.riken.jp/db/mgi_rdf/MGI:3717764

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(MMTV-KLF4)1Rup/0,Trp53<tm1Brd>/Trp53<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Trp53<tm1Brd>|Trp53<+>|Tg(MMTV-KLF4)1Rup

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S7/SvEvBrd * C57BL/6NTac * FVB/NJ * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal dermal layer morphology
  http://purl.obolibrary.org/obo/MP_0001243

文献

http://purl.org/net/cito/citesAsAuthority

• K Wade. Foster, et.al., Induction of KLF4 in basal keratinocytes blocks the proliferation-differentiation switch and initiates squamous epithelial dysplasia., Oncogene, 2005, 24
  http://rdf.ncbi.nlm.nih.gov/pubmed/15674344