thick dermal layer_Fbn1<tm3.1Hcd>/Fbn1<+>,Itgb3<tm1Hyn>/Itgb3<+>

http://metadb.riken.jp/0001245I129S129X1SvJC57BL6JFVBNFbn1tm31HcdFbn1Itgb3tm1HynItgb3Itgb3tm1HynFbn1Fbn1tm31HcdItgb3

thick dermal layer_Fbn1<tm3.1Hcd>/Fbn1<+>,Itgb3<tm1Hyn>/Itgb3<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• integrin beta 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:96612
• fibrillin 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:95489

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Fbn1<tm3.1Hcd>/Fbn1<+>,Itgb3<tm1Hyn>/Itgb3<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Itgb3<tm1Hyn>|Fbn1<+>|Fbn1<tm3.1Hcd>|Itgb3<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S * 129X1/SvJ * C57BL/6J * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• thick dermal layer
  http://purl.obolibrary.org/obo/MP_0001245

文献

http://purl.org/net/cito/citesAsAuthority

• Elizabeth E. Gerber, et.al., Integrin-modulating therapy prevents fibrosis and autoimmunity in mouse models of scleroderma., Nature, 2013, 503
  http://rdf.ncbi.nlm.nih.gov/pubmed/24107997