decreased body weight_Ctsd<tm1Cptr>/Ctsd<tm1Cptr>

http://metadb.riken.jp/0001262EI129P2OlaHsdC57BL6orI129P2OlaHsdCtsdtm1CptrCtsdtm1CptrCtsdtm1Cptr

decreased body weight_Ctsd<tm1Cptr>/Ctsd<tm1Cptr>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• cathepsin D
  http://metadb.riken.jp/db/mgi_rdf/MGI:88562

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ctsd<tm1Cptr>/Ctsd<tm1Cptr>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Ctsd<tm1Cptr>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd)

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased body weight
  http://purl.obolibrary.org/obo/MP_0001262

文献

http://purl.org/net/cito/citesAsAuthority

• P. Saftig, et.al., Mice deficient for the lysosomal proteinase cathepsin D exhibit progressive atrophy of the intestinal mucosa and profound destruction of lymphoid cells., The EMBO journal, 1995, 14
  http://rdf.ncbi.nlm.nih.gov/pubmed/7641679
• H. Nakanishi, et.al., Involvement of nitric oxide released from microglia-macrophages in pathological changes of cathepsin D-deficient mice., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2001, 21
  http://rdf.ncbi.nlm.nih.gov/pubmed/11567042