decreased body weight_Gna11<tm1Soff>/Gna11<+>,Gnaq<tm2Soff>/Gnaq<tm2Soff>,Tg(PTH-cre)4167Slib/0

http://metadb.riken.jp/0001262I129P2OlaHsd129S7SvEvBrdC57BL6Gna11tm1SoffGna11Gnaqtm2SoffGnaqtm2SoffTgPTHcre4167Slib0Gnaqtm2SoffGna11tm1SoffGna11TgPTHcre4167Slib

decreased body weight_Gna11<tm1Soff>/Gna11<+>,Gnaq<tm2Soff>/Gnaq<tm2Soff>,Tg(PTH-cre)4167Slib/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 4167, Steven K Libutti
  http://metadb.riken.jp/db/mgi_rdf/MGI:2683307
• guanine nucleotide binding protein, alpha 11
  http://metadb.riken.jp/db/mgi_rdf/MGI:95766
• guanine nucleotide binding protein, alpha q polypeptide
  http://metadb.riken.jp/db/mgi_rdf/MGI:95776

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gna11<tm1Soff>/Gna11<+>,Gnaq<tm2Soff>/Gnaq<tm2Soff>,Tg(PTH-cre)4167Slib/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gnaq<tm2Soff>|Gna11<tm1Soff>|Gna11<+>|Tg(PTH-cre)4167Slib

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased body weight
  http://purl.obolibrary.org/obo/MP_0001262

文献

http://purl.org/net/cito/citesAsAuthority

• Nina. Wettschureck, et.al., Parathyroid-specific double knockout of Gq and G11 alpha-subunits leads to a phenotype resembling germline knockout of the extracellular Ca2+ -sensing receptor., Molecular endocrinology (Baltimore, Md.), 2007, 21
  http://rdf.ncbi.nlm.nih.gov/pubmed/16988000