Nina. Wettschureck, et.al., Parathyroid-specific double knockout of Gq and G11 alpha-subunits leads to a phenotype resembling germline knockout of the extracellular Ca2+ -sensing receptor., Molecular endocrinology (Baltimore, Md.), 2007, 21

http://rdf.ncbi.nlm.nih.gov/pubmed/16988000

Nina. Wettschureck, et.al., Parathyroid-specific double knockout of Gq and G11 alpha-subunits leads to a phenotype resembling germline knockout of the extracellular Ca2+ -sensing receptor., Molecular endocrinology (Baltimore, Md.), 2007, 21

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased body weight_Gna11<tm1Soff>/Gna11<+>,Gnaq<tm2Soff>/Gnaq<tm2Soff>,Tg(PTH-cre)4167Slib/0
  http://metadb.riken.jp/0001262I129P2OlaHsd129S7SvEvBrdC57BL6Gna11tm1SoffGna11Gnaqtm2SoffGnaqtm2SoffTgPTHcre4167Slib0Gnaqtm2SoffGna11tm1SoffGna11TgPTHcre4167Slib
• abnormal circulating calcium level_Gna11<tm1Soff>/Gna11<+>,Gnaq<tm2Soff>/Gnaq<tm2Soff>,Tg(PTH-cre)4167Slib/0
  http://metadb.riken.jp/0001562I129P2OlaHsd129S7SvEvBrdC57BL6Gna11tm1SoffGna11Gnaqtm2SoffGnaqtm2SoffTgPTHcre4167Slib0Gnaqtm2SoffGna11tm1SoffGna11TgPTHcre4167Slib
• short snout_Gna11<tm1Soff>/Gna11<tm1Soff>,Gnaq<tm2Soff>/Gnaq<tm2Soff>,Tg(PTH-cre)4167Slib/0
  http://metadb.riken.jp/0000445I129P2OlaHsd129S7SvEvBrdC57BL6Gna11tm1SoffGna11tm1SoffGnaqtm2SoffGnaqtm2SoffTgPTHcre4167Slib0TgPTHcre4167SlibGna11tm1SoffGnaqtm2Soff
• increased bone resorption_Gna11<tm1Soff>/Gna11<tm1Soff>,Gnaq<tm2Soff>/Gnaq<tm2Soff>,Tg(PTH-cre)4167Slib/0
  http://metadb.riken.jp/0004992I129P2OlaHsd129S7SvEvBrdC57BL6Gna11tm1SoffGna11tm1SoffGnaqtm2SoffGnaqtm2SoffTgPTHcre4167Slib0TgPTHcre4167SlibGna11tm1SoffGnaqtm2Soff
• postnatal growth retardation_Gna11<tm1Soff>/Gna11<tm1Soff>,Gnaq<tm2Soff>/Gnaq<tm2Soff>,Tg(PTH-cre)4167Slib/0
  http://metadb.riken.jp/0001732I129P2OlaHsd129S7SvEvBrdC57BL6Gna11tm1SoffGna11tm1SoffGnaqtm2SoffGnaqtm2SoffTgPTHcre4167Slib0TgPTHcre4167SlibGna11tm1SoffGnaqtm2Soff
• abnormal urine calcium level_Gna11<tm1Soff>/Gna11<tm1Soff>,Gnaq<tm2Soff>/Gnaq<+>,Tg(PTH-cre)4167Slib/0
  http://metadb.riken.jp/0002985I129P2OlaHsd129S7SvEvBrdC57BL6Gna11tm1SoffGna11tm1SoffGnaqtm2SoffGnaqTgPTHcre4167Slib0GnaqGnaqtm2SoffGna11tm1SoffTgPTHcre4167Slib
• decreased bone mineral density_Gna11<tm1Soff>/Gna11<tm1Soff>,Gnaq<tm2Soff>/Gnaq<tm2Soff>,Tg(PTH-cre)4167Slib/0
  http://metadb.riken.jp/0000063I129P2OlaHsd129S7SvEvBrdC57BL6Gna11tm1SoffGna11tm1SoffGnaqtm2SoffGnaqtm2SoffTgPTHcre4167Slib0TgPTHcre4167SlibGna11tm1SoffGnaqtm2Soff
• abnormal rib development_Gna11<tm1Soff>/Gna11<tm1Soff>,Gnaq<tm2Soff>/Gnaq<tm2Soff>,Tg(PTH-cre)4167Slib/0
  http://metadb.riken.jp/0002823I129P2OlaHsd129S7SvEvBrdC57BL6Gna11tm1SoffGna11tm1SoffGnaqtm2SoffGnaqtm2SoffTgPTHcre4167Slib0TgPTHcre4167SlibGna11tm1SoffGnaqtm2Soff
• abnormal circulating calcium level_Gna11<tm1Soff>/Gna11<tm1Soff>,Gnaq<tm2Soff>/Gnaq<+>,Tg(PTH-cre)4167Slib/0
  http://metadb.riken.jp/0001562I129P2OlaHsd129S7SvEvBrdC57BL6Gna11tm1SoffGna11tm1SoffGnaqtm2SoffGnaqTgPTHcre4167Slib0GnaqGnaqtm2SoffGna11tm1SoffTgPTHcre4167Slib
• domed cranium_Gna11<tm1Soff>/Gna11<tm1Soff>,Gnaq<tm2Soff>/Gnaq<tm2Soff>,Tg(PTH-cre)4167Slib/0
  http://metadb.riken.jp/0000440I129P2OlaHsd129S7SvEvBrdC57BL6Gna11tm1SoffGna11tm1SoffGnaqtm2SoffGnaqtm2SoffTgPTHcre4167Slib0TgPTHcre4167SlibGna11tm1SoffGnaqtm2Soff
• small thyroid gland_Gna11<tm1Soff>/Gna11<tm1Soff>,Gnaq<tm2Soff>/Gnaq<tm2Soff>,Tg(PTH-cre)4167Slib/0
  http://metadb.riken.jp/0002951I129P2OlaHsd129S7SvEvBrdC57BL6Gna11tm1SoffGna11tm1SoffGnaqtm2SoffGnaqtm2SoffTgPTHcre4167Slib0TgPTHcre4167SlibGna11tm1SoffGnaqtm2Soff
• abnormal cranial suture morphology_Gna11<tm1Soff>/Gna11<tm1Soff>,Gnaq<tm2Soff>/Gnaq<tm2Soff>,Tg(PTH-cre)4167Slib/0
  http://metadb.riken.jp/0002835I129P2OlaHsd129S7SvEvBrdC57BL6Gna11tm1SoffGna11tm1SoffGnaqtm2SoffGnaqtm2SoffTgPTHcre4167Slib0TgPTHcre4167SlibGna11tm1SoffGnaqtm2Soff
• decreased body length_Gna11<tm1Soff>/Gna11<tm1Soff>,Gnaq<tm2Soff>/Gnaq<tm2Soff>,Tg(PTH-cre)4167Slib/0
  http://metadb.riken.jp/0001258I129P2OlaHsd129S7SvEvBrdC57BL6Gna11tm1SoffGna11tm1SoffGnaqtm2SoffGnaqtm2SoffTgPTHcre4167Slib0TgPTHcre4167SlibGna11tm1SoffGnaqtm2Soff
• abnormal bone mineralization_Gna11<tm1Soff>/Gna11<tm1Soff>,Gnaq<tm2Soff>/Gnaq<tm2Soff>,Tg(PTH-cre)4167Slib/0
  http://metadb.riken.jp/0002896I129P2OlaHsd129S7SvEvBrdC57BL6Gna11tm1SoffGna11tm1SoffGnaqtm2SoffGnaqtm2SoffTgPTHcre4167Slib0TgPTHcre4167SlibGna11tm1SoffGnaqtm2Soff
• abnormal larynx morphology_Gna11<tm1Soff>/Gna11<tm1Soff>,Gnaq<tm2Soff>/Gnaq<tm2Soff>,Tg(PTH-cre)4167Slib/0
  http://metadb.riken.jp/0002249I129P2OlaHsd129S7SvEvBrdC57BL6Gna11tm1SoffGna11tm1SoffGnaqtm2SoffGnaqtm2SoffTgPTHcre4167Slib0TgPTHcre4167SlibGna11tm1SoffGnaqtm2Soff
• decreased body weight_Gna11<tm1Soff>/Gna11<tm1Soff>,Gnaq<tm2Soff>/Gnaq<+>,Tg(PTH-cre)4167Slib/0
  http://metadb.riken.jp/0001262I129P2OlaHsd129S7SvEvBrdC57BL6Gna11tm1SoffGna11tm1SoffGnaqtm2SoffGnaqTgPTHcre4167Slib0GnaqGnaqtm2SoffGna11tm1SoffTgPTHcre4167Slib
• postnatal lethality_Gna11<tm1Soff>/Gna11<tm1Soff>,Gnaq<tm2Soff>/Gnaq<tm2Soff>,Tg(PTH-cre)4167Slib/0
  http://metadb.riken.jp/0002082I129P2OlaHsd129S7SvEvBrdC57BL6Gna11tm1SoffGna11tm1SoffGnaqtm2SoffGnaqtm2SoffTgPTHcre4167Slib0TgPTHcre4167SlibGna11tm1SoffGnaqtm2Soff
• abnormal epiphyseal plate morphology_Gna11<tm1Soff>/Gna11<tm1Soff>,Gnaq<tm2Soff>/Gnaq<tm2Soff>,Tg(PTH-cre)4167Slib/0
  http://metadb.riken.jp/0006395I129P2OlaHsd129S7SvEvBrdC57BL6Gna11tm1SoffGna11tm1SoffGnaqtm2SoffGnaqtm2SoffTgPTHcre4167Slib0TgPTHcre4167SlibGna11tm1SoffGnaqtm2Soff
• abnormal urine calcium level_Gna11<tm1Soff>/Gna11<+>,Gnaq<tm2Soff>/Gnaq<tm2Soff>,Tg(PTH-cre)4167Slib/0
  http://metadb.riken.jp/0002985I129P2OlaHsd129S7SvEvBrdC57BL6Gna11tm1SoffGna11Gnaqtm2SoffGnaqtm2SoffTgPTHcre4167Slib0Gnaqtm2SoffGna11tm1SoffGna11TgPTHcre4167Slib
• increased circulating parathyroid hormone level_Gna11<tm1Soff>/Gna11<tm1Soff>,Gnaq<tm2Soff>/Gnaq<tm2Soff>,Tg(PTH-cre)4167Slib/0
  http://metadb.riken.jp/0002904I129P2OlaHsd129S7SvEvBrdC57BL6Gna11tm1SoffGna11tm1SoffGnaqtm2SoffGnaqtm2SoffTgPTHcre4167Slib0TgPTHcre4167SlibGna11tm1SoffGnaqtm2Soff
• abnormal parathyroid gland morphology_Gna11<tm1Soff>/Gna11<tm1Soff>,Gnaq<tm2Soff>/Gnaq<tm2Soff>,Tg(PTH-cre)4167Slib/0
  http://metadb.riken.jp/0000678I129P2OlaHsd129S7SvEvBrdC57BL6Gna11tm1SoffGna11tm1SoffGnaqtm2SoffGnaqtm2SoffTgPTHcre4167Slib0TgPTHcre4167SlibGna11tm1SoffGnaqtm2Soff
• proportional dwarf_Gna11<tm1Soff>/Gna11<tm1Soff>,Gnaq<tm2Soff>/Gnaq<tm2Soff>,Tg(PTH-cre)4167Slib/0
  http://metadb.riken.jp/0008974I129P2OlaHsd129S7SvEvBrdC57BL6Gna11tm1SoffGna11tm1SoffGnaqtm2SoffGnaqtm2SoffTgPTHcre4167Slib0TgPTHcre4167SlibGna11tm1SoffGnaqtm2Soff
• delayed endochondral bone ossification_Gna11<tm1Soff>/Gna11<tm1Soff>,Gnaq<tm2Soff>/Gnaq<tm2Soff>,Tg(PTH-cre)4167Slib/0
  http://metadb.riken.jp/0003419I129P2OlaHsd129S7SvEvBrdC57BL6Gna11tm1SoffGna11tm1SoffGnaqtm2SoffGnaqtm2SoffTgPTHcre4167Slib0TgPTHcre4167SlibGna11tm1SoffGnaqtm2Soff
• increased circulating parathyroid hormone level_Gna11<tm1Soff>/Gna11<+>,Gnaq<tm2Soff>/Gnaq<tm2Soff>,Tg(PTH-cre)4167Slib/0
  http://metadb.riken.jp/0002904I129P2OlaHsd129S7SvEvBrdC57BL6Gna11tm1SoffGna11Gnaqtm2SoffGnaqtm2SoffTgPTHcre4167Slib0Gnaqtm2SoffGna11tm1SoffGna11TgPTHcre4167Slib
• increased urine calcium level_Gna11<tm1Soff>/Gna11<tm1Soff>,Gnaq<tm2Soff>/Gnaq<tm2Soff>,Tg(PTH-cre)4167Slib/0
  http://metadb.riken.jp/0005441I129P2OlaHsd129S7SvEvBrdC57BL6Gna11tm1SoffGna11tm1SoffGnaqtm2SoffGnaqtm2SoffTgPTHcre4167Slib0TgPTHcre4167SlibGna11tm1SoffGnaqtm2Soff
• increased circulating parathyroid hormone level_Gna11<tm1Soff>/Gna11<tm1Soff>,Gnaq<tm2Soff>/Gnaq<+>,Tg(PTH-cre)4167Slib/0
  http://metadb.riken.jp/0002904I129P2OlaHsd129S7SvEvBrdC57BL6Gna11tm1SoffGna11tm1SoffGnaqtm2SoffGnaqTgPTHcre4167Slib0GnaqGnaqtm2SoffGna11tm1SoffTgPTHcre4167Slib
• decreased body weight_Gna11<tm1Soff>/Gna11<tm1Soff>,Gnaq<tm2Soff>/Gnaq<tm2Soff>,Tg(PTH-cre)4167Slib/0
  http://metadb.riken.jp/0001262I129P2OlaHsd129S7SvEvBrdC57BL6Gna11tm1SoffGna11tm1SoffGnaqtm2SoffGnaqtm2SoffTgPTHcre4167Slib0TgPTHcre4167SlibGna11tm1SoffGnaqtm2Soff