increased metastatic potential_Cdkn2a<tm2.1Rdp>/Cdkn2a<tm2.1Rdp>,Kras<tm4Tyj>/Kras<+>

http://metadb.riken.jp/0001272I129S4SvJae129S6SvEvTacC57BL6FVBNCdkn2atm21RdpCdkn2atm21RdpKrastm4TyjKrasKrastm4TyjCdkn2atm21RdpKras

increased metastatic potential_Cdkn2a<tm2.1Rdp>/Cdkn2a<tm2.1Rdp>,Kras<tm4Tyj>/Kras<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• cyclin-dependent kinase inhibitor 2A
  http://metadb.riken.jp/db/mgi_rdf/MGI:104738
• Kirsten rat sarcoma viral oncogene homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:96680

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cdkn2a<tm2.1Rdp>/Cdkn2a<tm2.1Rdp>,Kras<tm4Tyj>/Kras<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Kras<tm4Tyj>|Cdkn2a<tm2.1Rdp>|Kras<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6 * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased metastatic potential
  http://purl.obolibrary.org/obo/MP_0001272

文献

http://purl.org/net/cito/citesAsAuthority

• Hongbin. Ji, et.al., LKB1 modulates lung cancer differentiation and metastasis., Nature, 2007, 448
  http://rdf.ncbi.nlm.nih.gov/pubmed/17676035